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Which pain block works best after hysterectomy? ultrasound, surgical, or local injection?

NCT ID NCT06837532

Symptom relief Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Aug 13, 2026 · Updated 3 times

Summary

This trial tests three methods of delivering the anesthetic bupivacaine to reduce pain after total abdominal hysterectomy: an ultrasound-guided rectus sheath block, a surgical rectus sheath block, or local infiltration. The study includes 90 adults aged 18–65 scheduled for elective surgery. The main goal is to see which approach lowers the need for morphine rescue pain relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If one method proves superior, it could become the standard for reducing pain and morphine use after hysterectomy.
What could go wrong
This is a small, single-center trial (90 patients), so results may not apply broadly. All methods carry typical risks of local anesthetics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Feb 2025

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age from 18 to 65 years old. * American Society of Anesthesiologists (ASA) physical status I - II. * Patients scheduled for elective total abdominal hysterectomy under general anesthesia. Exclusion Criteria: * Hepatic, renal or cardiac disease. * Any known allergy to local anesthetic. * Physical or mental conditions which may vaguely measure postoperative pain following surgery. * History of chronic use of analgesic as nonsteroidal anti-inflammatory drugs (NSAIDs) or central nervous system (CNS) depressants as antiepileptic, and bleeding disorders.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Local anesthesia infiltration Postoperative analgesia Rectus sheath block Surgical Total abdominal hysterectomy Ultrasound

Contacts and locations

Locations

  • Ain Shams University

    Cairo, 11591, Egypt

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