New pill could ease Post-Surgery pain without opioids

NCT ID NCT07185594

Recruiting now Symptom relief Sponsor: Shandong Suncadia Medicine Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new drug called HRS-2129 for managing pain after abdominal surgery. About 360 adults having abdominal surgery will receive either HRS-2129, a placebo, or the standard painkiller tramadol. The goal is to see if HRS-2129 works better or has fewer side effects than current options.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: HRS-2129 tablets
What this could lead to: If successful, this could provide a new option for managing pain after abdominal surgery, potentially with fewer side effects than current treatments.
What could go wrong: This is an early-to-mid-stage trial with only 360 participants. The drug may not prove more effective or safer than existing painkillers, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for POSTOPERATIVE ANALGESIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE ANALGESIA

Contacts and locations

Locations

The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, Henan, 450052, China
The Second Affiliated Hospital of Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310009, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.