New Long-Acting numbing shot could ease pain after major abdominal surgery

NCT ID NCT07667439

Not yet recruiting Symptom relief Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a long-acting numbing drug (liposomal bupivacaine) can reduce pain for up to 72 hours after open upper abdominal surgery. 148 adults having liver, stomach, or pancreatic surgery will get either the long-acting drug plus standard numbing, or standard numbing alone. The goal is to see if the long-acting version provides better and safer pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: liposomal bupivacaine plus bupivacaine hydrochloride
What this could lead to: If it works, this could provide a longer-lasting, safer way to manage pain after major abdominal surgery, reducing the need for strong painkillers.
What could go wrong: This is a small, early-stage trial (148 people) at one hospital. The benefit may be small or not apply to all surgeries, and there is a risk of side effects like nausea or dizziness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ERECTOR SPINAE PLANE BLOCK LIPOSOME BUPIVACAINE POSTOPERATIVE ANALGESIA RANDOMIZED CONTROLLED TRIAL

Contacts and locations

Locations

the Second Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, China

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