New Long-Acting numbing shot could ease pain after major abdominal surgery

NCT ID NCT07667439

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a long-acting numbing drug (liposomal bupivacaine) can reduce pain for up to 72 hours after open upper abdominal surgery. 148 adults having liver, stomach, or pancreatic surgery will get either the long-acting drug plus standard numbing, or standard numbing alone. The goal is to see if the long-acting version provides better and safer pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

liposomal bupivacaine plus bupivacaine hydrochloride

What this could lead to

If it works, this could provide a longer-lasting, safer way to manage pain after major abdominal surgery, reducing the need for strong painkillers.

What could go wrong

This is a small, early-stage trial (148 people) at one hospital. The benefit may be small or not apply to all surgeries, and there is a risk of side effects like nausea or dizziness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for POSTOPERATIVE ANALGESIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • the Second Affiliated Hospital, Zhejiang University School of Medicine

    Hangzhou, China

    Contact Email: •••••@•••••

    Contact