Personalizing sleep apnea treatment: a step toward better CPAP outcomes

NCT ID NCT05067088

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study investigates whether individual physiological traits that cause obstructive sleep apnea (OSA) can predict how well CPAP therapy works. Researchers will follow adults newly diagnosed with OSA who are starting CPAP, measuring factors like arousal threshold and breathing stability. The goal is to see if these traits influence CPAP adherence and effectiveness, potentially leading to more personalized treatment plans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Continuous positive airway pressure (CPAP) therapy
What this could lead to
If successful, this could lead to personalized OSA treatments, improving CPAP adherence and outcomes for millions.
What could go wrong
The study is observational and early, so findings may not translate into immediate clinical changes. Individual responses to CPAP vary, and the physiological traits measured may not fully predict effectiveness.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Yale New Haven Hospital Sleep Center

    North Haven, Connecticut, 06473, United States

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Other studies related to the condition(s) this trial covers.