Insomnia pill meets antidepressant: safety check underway

NCT ID NCT06680531

Completed Knowledge-focused Sponsor: Shanghai Haiyan Pharmaceutical Technology Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study examines whether a new insomnia drug, YZJ-1139, can be safely taken with the antidepressant escitalopram. Healthy adults aged 18 to 45 will receive both drugs and be monitored for side effects, drug levels in the blood, and changes in eye movements, balance, and thinking. The goal is to understand if combining these medications causes any unwanted interactions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: YZJ-1139 tablets and escitalopram oxalate tablets
What this could lead to: If safe together, this could guide future use of YZJ-1139 in people who also take antidepressants like escitalopram.
What could go wrong: This is a small, early-phase study in healthy volunteers, not patients. Results may not predict real-world safety or effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

central nervous system disorder insomnia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CENTRAL NERVOUS SYSTEM INSOMNIA

Contacts and locations

Locations

The Second Affiliated Hospital of Guangzhou Medical University

Guangzhou, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.