Insomnia pill meets antidepressant: safety check underway
NCT ID NCT06680531
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study examines whether a new insomnia drug, YZJ-1139, can be safely taken with the antidepressant escitalopram. Healthy adults aged 18 to 45 will receive both drugs and be monitored for side effects, drug levels in the blood, and changes in eye movements, balance, and thinking. The goal is to understand if combining these medications causes any unwanted interactions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
YZJ-1139 tablets and escitalopram oxalate tablets
What this could lead to
If safe together, this could guide future use of YZJ-1139 in people who also take antidepressants like escitalopram.
What could go wrong
This is a small, early-phase study in healthy volunteers, not patients. Results may not predict real-world safety or effectiveness.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Second Affiliated Hospital of Guangzhou Medical University
Guangzhou, China