Tomato-Based melatonin pill puts sleep to the test

NCT ID NCT07669766

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tested whether a plant-based melatonin supplement (phytomelatonin) from tomatoes can improve sleep quality better than synthetic melatonin or a placebo. 244 adults with poor sleep took one capsule nightly for 28 days. Sleep was tracked with a wearable ring and questionnaires to see which option worked best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Phytomelatonin (plant-based melatonin from tomatoes)

What this could lead to

If it works, this could offer a natural alternative to synthetic melatonin for improving sleep quality.

What could go wrong

This is a small, completed study with no phase designation, so results may not be conclusive or generalizable. The plant-based dose is lower than the synthetic one, which could limit effectiveness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • N/A Decentralized Trial - address for CRO headquarters, not the study location

    Wilmington, Delaware, 19808, United States