Jaw pain relief? PRP and hyaluronic acid injections show promise in small study
NCT ID NCT07643402
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested a combination of platelet-rich plasma (PRP) from the patient's own blood and hyaluronic acid injected into the jaw joint. Twenty-two adults with painful clicking and limited mouth opening received the treatment. Researchers used a jaw tracking device to measure changes in movement, pain, and how wide they could open their mouth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Platelet-rich plasma (PRP) and hyaluronic acid
What this could lead to
If it works, this could offer a non-surgical option to reduce jaw pain and improve mouth opening for people with jaw joint problems.
What could go wrong
This was a small, completed study with only 22 people and no control group. Results may not apply to everyone, and injections can cause temporary soreness or swelling.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Faculty of Dentistry, Mansoura university
Al Mansurah, Dakahlia Governorate, 35516, Egypt