Can a single Anti-Inflammatory injection boost jaw joint relief?

NCT ID NCT07743684

First seen Aug 04, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This trial tests whether adding a single injection of the anti-inflammatory drug meloxicam to a standard jaw joint washout procedure (arthrocentesis) improves outcomes for people with painful jaw joint problems. Half of the 50 adult participants will receive the combined treatment, while the other half will receive arthrocentesis alone. Over 12 weeks, researchers will measure pain, how wide the mouth can open, joint sounds, and patient satisfaction to see if the added drug makes a meaningful difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Arthrocentesis (joint washout) followed by a single intra-articular injection of meloxicam, an anti-inflammatory drug
What this could lead to
If adding meloxicam to arthrocentesis works, it could offer a more effective, minimally invasive treatment for stubborn TMJ pain and jaw stiffness, potentially reducing the need for more invasive surgery.
What could go wrong
This is a small, early-stage trial with only 50 participants, so results may not apply broadly. The benefit of adding meloxicam might be modest or no better than arthrocentesis alone, and there is a small risk of injection-related side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Al-Yarmook teaching hospital

    RECRUITING

    Baghdad, Iraq

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