Heart drug may alter sleep medication levels in the body

NCT ID NCT06671470

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study examines whether ticagrelor, a heart medication, changes how the body absorbs and processes YZJ-1139, an experimental insomnia treatment. Healthy volunteers aged 18 to 45 will take YZJ-1139 alone and then with ticagrelor to compare drug levels and safety. The goal is to understand potential interactions before the sleep drug is used in people who also need heart medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
YZJ-1139 and ticagrelor
What this could lead to
If successful, this could help determine safe dosing when YZJ-1139 is taken with ticagrelor.
What could go wrong
This is an early-phase drug interaction study in healthy people, not patients with insomnia. Results may not predict real-world use or effectiveness.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shulan (Hangzhou) Hospital

    Huangzhou, China

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Other studies related to the condition(s) this trial covers.