New sleep drug shows promise for liver patients

NCT ID NCT07480096

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a sleep medication called lemborexant in 82 adults with liver cirrhosis who had trouble sleeping. The drug works by blocking wakefulness signals in the brain. Researchers measured sleep quality and checked for side effects on the liver. The goal was to see if lemborexant is a safe and effective option for this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lemborexant

What this could lead to

If it works, this could offer a safer sleep medication for people with liver cirrhosis, improving their quality of life without harming the liver.

What could go wrong

This is a small, early-phase trial (82 participants). The results may not apply to all cirrhosis patients, and long-term safety is not yet known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis hepatic encephalopathy insomnia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hepatobiliary Division, Internal Medicine Department, Dr Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta

    Jakarta, DKI Jakarta, 10430, Indonesia