Poop pills for better sleep? new study tests gut bacteria transplant for insomnia

NCT ID NCT05917379

Completed Disease control Sponsor: Peking University Sixth Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested if transplanting healthy gut bacteria (fecal microbiota) can help people with chronic insomnia. 80 adults received either the bacteria or a placebo in capsules. Researchers measured sleep quality using sleep tests and questionnaires to see if the treatment improved sleep.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Cognitive Dysfunction Depression depressive disorder insomnia sleep disorder sleep-wake disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY COGNITIVE IMPAIRMENT DEPRESSION FECAL MICROBIOTA TRANSPLANTATION INSOMNIA CHRONIC SLEEP DISORDER

Contacts and locations

Locations

Department of Physical Therapy, The Second Affiliated Hospital of Xinxiang Medical University

Xinxiang, Henan, 453002, China
Department of Psychiatry, First Hospital of Shanxi Medical University

Taiyuan, Shanxi, 030001, China
Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 400016, China
Department of Psychiatry, The Second Affiliated Hospital of Anhui Medical University

Hefei, Anhui, 230601, China
Hefei Fourth People's Hospital/Anhui Mental Health Center

Hefei, Anhui, 230022, China
Institute of Brain Science and Brain-inspired Research, Shandong First Medical University and Shandong Academy of Medical Sciences

Jinan, Shandong, 250117, China
Peking University Six Hospital

Beijing, Beijing Municipality, 100191, China

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