New sleep aid aims to outperform standard insomnia treatment

NCT ID NCT06975514

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This clinical trial tests whether a new drug called YZJ-1139 can help people with insomnia sleep better than the commonly used medication zolpidem. Adults aged 18 to 64 with insomnia disorder take either YZJ-1139 or zolpidem daily for 28 days. Researchers measure sleep quality using both overnight sleep lab tests and daily sleep diaries to see which drug works better and is safer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

YZJ-1139

What this could lead to

If successful, YZJ-1139 could offer a new treatment option for people with insomnia, potentially improving sleep quality with fewer side effects than current medications.

What could go wrong

This is a Phase 3 trial, but results may not show a significant advantage over zolpidem. Side effects and individual responses vary, and long-term safety is not yet fully known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

insomnia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ChengDu Second People's Hospital

    Chengdu, China

  • ChongQing Traditional Chinese Medicine Hospital

    Chongqing, China

  • Deyang People's Hospital

    Deyang, China

  • Peking University People's Hospital

    Beijing, China

  • ShengJing Hospital Of China Medical University

    Shenyang, China

  • SuZhou GuangJi Hospital

    Suzhou, China

  • The First Affiliated Hospital of Jinan University (Guangzhou Overseas Chinese Hospital)

    Guangzhou, China

  • The First Affiliated Hospital of Ningbo University

    Ningbo, China

  • The First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital)

    Jinan, China

  • The Second Affiliated Hospital Of NanChang University

    Nanchang, China

  • The Second Affiliated Hospital of Soochow University

    Suzhou, China

  • The Second Affiliated Hospital of Zhengzhou University

    Zhengzhou, China

  • The Third Hospital of Hebei Medical University

    Shijiazhuang, China

  • Tianjin Anding Hospital

    Tianjin, China

  • Wuhan No.1 Hospital

    Wuhan, China

  • Yan'an University Xianyang Hospital

    Yan’an, China