Could treating sleep apnea help prevent Alzheimer's? new study investigates
NCT ID NCT05094271
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 1 study looked at whether obstructive sleep apnea (OSA) might contribute to Alzheimer's disease. Researchers studied 182 older adults aged 65-85 with and without OSA, using brain scans and breathing tests. The goal was to understand how sleep disruptions like apnea could affect Alzheimer's-related brain changes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Supplemental oxygen and continuous positive airway pressure (CPAP) machine
- What this could lead to
- If successful, this study could help clarify whether treating sleep apnea might slow or prevent Alzheimer's disease.
- What could go wrong
- This is an early, completed study focused on understanding the link, not testing a treatment. Results may not lead to direct clinical changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UCSD Sleep Research
La Jolla, California, 92037, United States
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