SLEEP APNEA

This study is testing whether a daytime sleep study works as well as an overnight one for adjusting a sleep apnea treatment device. The device is an implanted nerve stimulator that helps keep the airway open during sleep. Researchers will compare results from 110 patients who hav…

This study is testing whether three different treatments—oxygen, finasteride, and acetazolamide—can help control sleep apnea in elderly Veterans. Researchers want to see if these options can stabilize nighttime breathing and serve as alternatives to standard mask-based therapy. T…

This study is testing whether a new implanted nerve stimulation device called the Lunair Alpha System is safe and can help people with moderate to severe sleep apnea. It's for people who can't tolerate or don't have access to standard treatments like CPAP machines. Researchers wi…

This study aims to understand how weight-loss surgery helps control health problems linked to severe obesity, such as type 2 diabetes and sleep apnea. Researchers will follow 35 patients who are already scheduled for a specific type of weight-loss surgery (mini-gastric bypass) as…

This study is testing if a drug called bexagliflozin, already used for diabetes, can help reduce the severity of sleep apnea. Over 160 overweight or obese adults with moderate to severe sleep apnea will take either the drug or a placebo pill daily for six months. Researchers will…

This study aims to find better ways to control sleep-disordered breathing in people with chronic neck-level spinal cord injuries. Researchers are testing if giving supplemental oxygen or the medication trazodone can reduce breathing pauses and improve sleep quality. The study inv…

This VA study is testing whether daily breathing exercises can help people with spinal cord injuries who also have sleep apnea. Researchers want to see if breathing air with slightly more carbon dioxide for short periods can strengthen breathing muscles and reduce sleep apnea sev…

This study is testing three different medications (sivopixant, acetazolamide, and SASS-001) to see if they can improve breathing during sleep for adults with sleep apnea that has a central component. The trial will involve 60 participants who have sleep apnea along with certain h…

This study is testing a small, implanted device called the remedē Dual Channel System for people with severe sleep apnea. The device sends mild electrical signals to nerves to help keep the airway open during sleep. Researchers want to see if the device can be safely implanted an…

This study is creating a national registry in Belgium to track the long-term results of an implanted device for obstructive sleep apnea. The device, called Inspire, stimulates a nerve to keep the airway open during sleep. Researchers will follow 225 patients for five years to see…

This study is creating a large Spanish registry to better understand sleep apnea and daytime sleepiness. It will follow 1000 adults with suspected sleep apnea for two years, collecting health data and tracking how well treatments like CPAP machines work. The goal is to gather rea…

This study aims to understand how sleep apnea contributes to the development of diabetes. Researchers will study 300 people who have both prediabetes and sleep apnea under different lab conditions to see how their bodies process sugar. The goal is to learn the underlying biologic…