Could oxygen or a common drug fix Opioid-Linked sleep apnea?
NCT ID NCT05589753
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study investigates whether oxygen and the drug acetazolamide can help stabilize breathing during sleep in people who take prescription opioids and have sleep apnea. Researchers will measure breathing patterns and sleep quality in 150 veterans. The goal is to find new ways to treat sleep-disordered breathing linked to opioid use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oxygen and acetazolamide
What this could lead to
If successful, this could point toward new, non-opioid treatments for sleep apnea in people who rely on opioid medications, potentially improving sleep and overall health.
What could go wrong
This is an early-phase study with a small number of participants, so results may not apply to everyone. Acetazolamide can cause side effects like tingling, nausea, or electrolyte imbalances.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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John D. Dingell VA Medical Center, Detroit, MI
RECRUITINGDetroit, Michigan, 48201-1916, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact