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Could removing tonsils supercharge a sleep apnea implant?

NCT ID NCT07724938

Not yet recruiting Disease control Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether removing the tonsils at the same time as implanting a hypoglossal nerve stimulator improves treatment for obstructive sleep apnea in adults whose airway collapses from the side during sleep. Participants are randomly assigned to receive the nerve stimulator either with or without tonsillectomy. The study measures changes in sleep-study results and airway stability to see if the combination offers greater benefit.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a combination of tonsillectomy (surgical removal of the tonsils) and hypoglossal nerve stimulation (an implanted device that stimulates a nerve to keep the airway open during sleep)
What this could lead to
If the combination works better than nerve stimulation alone, it could offer a more effective surgical option for people with obstructive sleep apnea whose airway collapses from the side.
What could go wrong
This is a relatively small, early-stage trial, and the added benefit of tonsillectomy may be modest or absent. Tonsillectomy carries risks like bleeding, pain, and infection.

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Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBSTRUCTIVE SLEEP APNEA SLEEP DISORDERED BREATHING

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.