New hope for better sleep after spinal injury

NCT ID NCT02922894

Recruiting now Symptom relief Sponsor: John D. Dingell VA Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests three approaches—oxygen therapy, the drug trazodone, and brief low-oxygen episodes—to see if they can improve sleep apnea in people with chronic cervical spinal cord injury. Researchers will measure changes in breathing and sleep quality in 100 participants. The goal is to find a safe, effective way to ease sleep-disordered breathing in this population.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Trazodone, supplemental oxygen, and acute episodic hypoxia
What this could lead to: If successful, this could point toward a simple treatment to improve sleep and breathing in people with spinal cord injury.
What could go wrong: This is a small, early-phase study with only 100 participants, and the treatments may not work or could cause side effects like drowsiness or discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

central sleep apnea syndrome sleep apnea syndrome spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SLEEP APNEA SPINAL CORD INJURY

Contacts and locations

Locations

John D. Dingell VA Medical Center
RECRUITING

Detroit, Michigan, 48201, United States

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