New hope for better sleep after spinal injury

NCT ID NCT02922894

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests three approaches—oxygen therapy, the drug trazodone, and brief low-oxygen episodes—to see if they can improve sleep apnea in people with chronic cervical spinal cord injury. Researchers will measure changes in breathing and sleep quality in 100 participants. The goal is to find a safe, effective way to ease sleep-disordered breathing in this population.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Trazodone, supplemental oxygen, and acute episodic hypoxia

What this could lead to

If successful, this could point toward a simple treatment to improve sleep and breathing in people with spinal cord injury.

What could go wrong

This is a small, early-phase study with only 100 participants, and the treatments may not work or could cause side effects like drowsiness or discomfort.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

central sleep apnea syndrome sleep apnea syndrome spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • John D. Dingell VA Medical Center

    RECRUITING

    Detroit, Michigan, 48201, United States

    Contact Phone: •••-•••-••••