Nattokinase: a natural sleep and heart booster?

NCT ID NCT07229521

Recruiting now Symptom relief Sponsor: Taipei Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking nattokinase, a supplement made from fermented soybeans, can improve sleep quality, thinking skills, and heart health in people at risk for metabolic syndrome. About 80 adults will take either the supplement or a placebo for 12 weeks, then switch after a break. Researchers will measure sleep, mood, memory, and blood markers to see if the supplement helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nattokinase (a dietary supplement from fermented soybeans)
What this could lead to: If it works, this could point toward a simple supplement to improve sleep, thinking, and heart health in people with metabolic syndrome risk.
What could go wrong: This is a small, early-stage crossover trial with only 80 participants. Results may not apply to everyone, and the supplement may not work better than a placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome metabolic syndrome X Parasomnias sleep apnea syndrome sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METABOLIC SYNDROME SLEEPING DISORDERS

Contacts and locations

Locations

Taipei Medical University
RECRUITING

Taipei, 110, Taiwan

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