Female reproductive system disorder

This early-stage study tested a vaccine called DCP-001 in 17 women with a serious type of ovarian cancer who had already completed standard treatment. The goal was to see if the vaccine is safe and can boost the immune system to recognize and fight cancer cells. Researchers measu…

This trial investigates an experimental oral drug, LY3143921 hydrate, which blocks a protein called Cdc7 that cancer cells need to divide. It is being tested in adults with advanced solid tumours, including colorectal, ovarian, lung, and pancreatic cancers, that have not responde…

This trial tests whether a daily dienogest tablet can shrink endometriomas (ovarian cysts caused by endometriosis) and ease period pain better than a combined oral contraceptive pill. Women aged 18 to 40 with symptomatic endometriomas will take one of the two treatments for three…

This study tests an HPV vaccine (PRGN-2009) alone or with a drug called M7824 in people with HPV-positive cancers like cervical, anal, and throat cancers. The goal is to find a safe dose and see if the combination boosts the immune system's attack on tumors. The trial includes 39…

This early-phase trial tested a combination of two chemotherapy drugs (gemcitabine and carboplatin) plus lenalidomide, a drug that blocks blood vessel growth in tumors, in 18 adults with advanced solid tumors, especially urothelial (bladder) cancer. The main goal was to find the …

This study looks at whether a traditional Chinese herbal formula, Guishen Yijing, can help women with diminished ovarian reserve (DOR) — a condition where the ovaries have fewer eggs than expected for a woman's age. Researchers will review medical records of 126 women who took th…

This trial tests whether elagolix, a hormone-blocking drug, can shrink endometriomas (ovarian cysts caused by endometriosis) and ease severe period pain better than the combined birth control pill. Women aged 18-40 with symptomatic endometriomas (2-5 cm) will take either elagolix…

This trial is testing a procedure called HIPEC, where a heated chemotherapy drug (cisplatin) is delivered directly into the abdomen after surgery to remove visible cancer. The goal is to find the safest dose that can be used in patients with advanced ovarian, fallopian tube, or p…

This trial compares two surgical strategies for managing placenta accreta, a condition where the placenta grows too deeply into the uterine wall and can cause severe bleeding during delivery. One approach is a caesarean hysterectomy, which removes the uterus after the baby is bor…

This virtual trial tests whether a daily prebiotic and probiotic supplement can relieve symptoms of bacterial vaginosis and yeast infections, such as itching, odor, and abnormal discharge. Women aged 25 and older with these concerns will take two capsules daily for 30 days. The s…

This phase 1 trial is testing whether adding the antiviral drug Vistide (cidofovir) to the standard combination of radiation and chemotherapy can improve outcomes for people with HPV-positive cervical cancer. The idea is that Vistide may make cancer cells more sensitive to radiat…

This early-phase study tested an experimental drug called COM902, alone or with other drugs, in 94 people with advanced cancers like ovarian, lung, and colon cancer. The main goal was to check safety and find the right dose. Researchers also looked for early signs that the drug m…

This study tests whether giving an anti-inflammatory drug (anti-TNFα) a few days before a frozen embryo transfer can help women with endometriosis who have had a failed IVF cycle get pregnant. The trial involves 145 participants and compares the clinical pregnancy rate to standar…

This early-stage trial is testing whether combining two experimental immunotherapy drugs, zalifrelimab and balstilimab, can help shrink or control advanced solid tumors, including cervical cancer. The drugs are designed to block different 'brakes' on the immune system, potentiall…

This study looked at whether giving heated chemotherapy directly into the abdomen during a second-look surgery is possible for people with ovarian, fallopian tube, or peritoneal cancer. Ten participants who had already received standard treatment were enrolled. The goal was to se…

This phase II trial is testing whether the chemotherapy drug eribulin, given alone or combined with the immunotherapy pembrolizumab, can help people with ovarian or uterine carcinosarcoma that has returned or progressed. The study aims to see if these treatments can shrink tumors…

This phase II trial tested two immunotherapy drugs, durvalumab and tremelimumab, in 100 women with ovarian, fallopian tube, or peritoneal cancer that had come back or stopped responding to platinum-based chemotherapy. The study compared giving the drugs together versus one after …

This study tested a drug called trametinib in 260 people with low-grade ovarian or peritoneal cancer that returned or worsened. Trametinib works by blocking certain enzymes that help cancer cells grow. The goal was to see if it works better than standard treatments like hormone t…

This pilot study tested whether women with kidney infections could safely stop antibiotics once their symptoms resolved, instead of taking a full 10-day course. 35 women were randomly assigned to either standard treatment or a patient-directed approach. The main goal was to see i…

This trial tests whether a 7-day antibiotic course—starting with an intravenous dose of ceftriaxone followed by oral cefixime—can effectively treat acute uncomplicated pyelonephritis (a kidney infection) in women aged 18 to 65. The goal is to see if this shorter regimen works as …

This phase 2 trial tests the drug cabozantinib in women with advanced or metastatic cervical cancer that has worsened after platinum-based chemotherapy. The study aims to see if cabozantinib can control the disease and how safe it is, particularly regarding risks like fistulas. P…

This trial tests whether a daily dietary supplement called WeNatal For Her can improve markers of female fertility in women who are trying to conceive. Forty women aged 18-45 will take three capsules each morning for three menstrual cycles. Researchers will measure blood levels o…

This trial compares two ways to make the first incision for laparoscopic surgery in women with endometrial cancer: the standard umbilical entry versus entry through the Lee-Huang point, a spot on the upper left abdomen. The goal is to see which approach leads to fewer complicatio…

This trial tests whether taking a specific probiotic supplement (Lactobacillus crispatus Lc-G22) alongside standard antifungal treatment can help prevent repeat vaginal yeast infections. One hundred women with a history of frequent yeast infections will receive either the probiot…

This trial tests whether a soft balloon (Cook's balloon) placed in the cervix is better than a vaginal medication (dinoprostone) for starting labor in full-term pregnancies where the baby is growing slowly. The main goal is to see which method leads to more vaginal deliveries and…

This trial tests an experimental drug, RSO-021, given directly into the chest cavity of people with malignant pleural effusion—a buildup of fluid around the lungs caused by advanced solid tumors or mesothelioma. The study aims to find a safe dose and check for early signs that th…

This study monitors the safety and effectiveness of the drug olaparib (Lynparza) in people with ovarian, breast, prostate, or pancreatic cancer who are prescribed it as part of routine care in South Korea. Researchers will track side effects and how long the cancer stays under co…

This phase II trial tests whether combining two hormone-blocking drugs — onapristone and anastrozole — can shrink tumors or slow cancer growth in women with hormone-receptor-positive endometrial cancer that has not responded to prior chemotherapy. Onapristone blocks progesterone …

This trial tests an experimental drug called enfortumab vedotin, which is designed to seek out and destroy cancer cells that have a specific protein called Nectin-4 on their surface. The study includes people with metastatic urothelial cancer (a type of bladder cancer) and other …

This study tests whether extremely low birth weight infants (born before 29 weeks) who receive donor human milk during their hospital stay have better brain development than those given preterm formula. Infants whose mothers cannot or choose not to breastfeed are randomly assigne…

This early-phase trial tests whether injecting tiny particles called extracellular vesicles, derived from bone marrow stem cells, directly into the ovary is safe for women with premature ovarian failure. The study includes 10 women aged 20–38 who have had no menstrual period for …

This study compares two surgical approaches for laparoscopic hysterectomy in women with benign or premalignant uterine conditions. One method uses a single incision through the belly button, while the other uses three to four small abdominal cuts. The goal is to see which techniq…

This phase 4 trial tests whether a daily combination of myo-inositol and D-chiro-inositol (with folic acid) can improve menstrual regularity and hormone levels in women with polycystic ovary syndrome (PCOS). Sixty women aged 18–45 with PCOS will receive either the inositol combin…

This study compares four surgical techniques to temporarily block blood flow to the uterus during laparoscopic fibroid removal. The goal is to see which method best reduces blood loss and protects ovarian function. Sixty women with uterine fibroids will be randomly assigned to on…

This study tests a new drug called pegilodecakin, a lab-made version of a natural immune protein (interleukin-10), in people with advanced solid tumors such as melanoma, lung, breast, prostate, ovarian, kidney, colorectal, and pancreatic cancers. The drug is given as a daily shot…

This study looked at over 1,100 women who had surgery for ovarian endometriomas (cysts caused by endometriosis) and then took one of four hormonal treatments to prevent recurrence. The goal was to see which treatment—birth control pills, GnRH agonists, dienogest, or dydrogesteron…

This phase II trial investigates whether adding the immunotherapy drug pembrolizumab (Keytruda) to standard chemotherapy (carboplatin and paclitaxel) improves outcomes for people with advanced stage III-IV ovarian, fallopian tube, or primary peritoneal cancer. The study aims to s…

This trial investigates whether taking a postbiotic supplement daily for four weeks can help ease symptoms of vaginal yeast infections in women. Participants are sexually active women with a confirmed yeast infection. The study compares the postbiotic to a placebo to see if it im…

This early-stage trial is testing a combination of two lab-made antibodies in people with advanced solid tumors that have not responded to standard treatments. One antibody (LDP) aims to reactivate the immune system against cancer, while the other (CDP1) blocks a growth signal on…

This phase II trial tests whether the drug RAD001 can shrink or slow the growth of tumors in people with recurrent endometrial cancer. Participants take RAD001 daily by mouth. The study measures how many patients have their tumors shrink or stay stable, and also tracks side effec…

This study tests whether a secure website with educational sessions, goal-setting, and tracking tools can help survivors of several cancers (including breast, prostate, colorectal, and others) improve their diet, increase physical activity, and manage weight. Participants are age…

This trial tests whether combining a hormone-releasing IUD with an anchoring IUD can prevent the device from slipping out of place in women with adenomyosis, a condition that causes pelvic pain and heavy bleeding. The study includes 270 women with different uterine cavity depths,…

This trial compares three modern radiotherapy techniques—helical tomotherapy and two types of dynamic arc therapy (RapidArc and VMAT)—for treating prostate, cervical, and anal canal cancers that require pelvic lymph node irradiation. The goal is to determine which method is most …

This trial tests whether repeatedly adding sterile fluid into the womb can help fetuses with severe kidney failure grow enough lungs to survive after birth. Pregnant women with early pregnancy kidney failure can choose to receive the infusions or just be monitored. Babies who sur…

This study tests whether using continuous positive airway pressure (CPAP) or positive end-expiratory pressure (PEEP) during resuscitation helps extremely low birth weight infants (born before 28 weeks) breathe better and avoid lung damage. Half of the babies receive standard care…

This early-phase study tested the safety of combining two drugs—pembrolizumab (an immunotherapy) and AMG386 (which targets blood vessel growth)—in 62 people with advanced solid tumors like melanoma, ovarian, renal, or colorectal cancer. The main goals were to find the safest dose…

This study tests a combination of three immunotherapy drugs—PDS0101, M7824, and NHS-IL12—in people with advanced HPV-related cancers such as cervical, anal, and throat cancers. The goal is to see if the mix can shrink tumors or stop them from growing. Participants receive the dru…

This early-stage trial tested a DNA vaccine called NWRD08 in 9 women with high-grade cervical lesions caused by HPV types 16 or 18. The vaccine was given as a shot followed by a mild electrical pulse to help cells take it up. The main goal was to check safety and see if the vacci…

This phase 2 trial tested a combination of two drugs—paclitaxel (given intravenously and directly into the abdomen) and oral nilotinib—in 21 adults with cancers that had spread to the lining of the abdomen and could not be surgically removed. The goal was to see if the treatment …

This study tested the drug pembrolizumab (Keytruda) as a follow-up treatment for one patient with a rare type of ovarian cancer called small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). The goal was to see if the drug could help keep the cancer from coming back. Beca…

This pilot study tested whether waiting 30-45 seconds before clamping the umbilical cord, instead of clamping immediately, is feasible and might improve blood health in extremely low birth weight premature infants (24-27 weeks gestation). 54 infants were enrolled. The goal was to…

This early-phase trial tested an experimental drug called KVA12123, given alone or with the immunotherapy Keytruda, in 40 adults with advanced solid tumors (like lung, breast, or colon cancer) that had stopped responding to standard treatments. The main goals were to check safety…

This study looked at when to start giving a drug called rhTPO to cervical cancer patients whose platelet levels drop during chemoradiation. The goal was to see if starting treatment earlier could prevent severe low platelet counts. Researchers studied 75 patients and compared two…

This study compares a new formulation of the chemotherapy drug doxorubicin (Doxopeg) to the standard version (Caelyx) in people with advanced ovarian cancer or metastatic breast cancer. The goal is to see if the two drugs are absorbed and processed by the body in the same way. Pa…

This completed phase 2 trial tested whether the drug cediranib, given with chemotherapy, is safe for women with advanced ovarian cancer who are at risk of bowel obstruction. 30 participants received the combination. The study focused on whether the treatment caused serious bowel …

This study tested a new immunotherapy called Olvi-Vec, which uses a modified virus to attack cancer cells, in 46 patients with ovarian cancer that had come back or stopped responding to standard treatments. The goal was to see if the treatment was safe and could slow tumor growth…

This Phase 3 trial tested whether taking Elagolix (a hormone-blocking pill) for two months before IVF could improve live birth rates in women with endometriosis. 103 women participated, and the main goal was to see if more babies were born after this pre-treatment. The study comp…

This study tested a drug called SB-UF, which combines hormones and a plant extract, to see if it can shrink uterine fibroids in pregnant women. 66 women took the drug or a placebo throughout their pregnancy. The goal was to reduce fibroid size and help them disappear, which could…

This early-phase trial tested a new type of vaccine made from a patient's own immune cells (dendritic cells) that are engineered to target a protein called WT1 found in many cancers. Ten people with advanced esophageal, pancreatic, ovarian, or liver cancer received six vaccines o…

This study tested a new type of radiation therapy that adjusts the treatment plan daily based on the patient's anatomy. It included 15 women with endometrial or cervical cancer who had surgery and needed radiation. The goal was to see if smaller treatment margins could be used sa…

This early-phase study tested whether adding indomethacin, a common anti-inflammatory drug, to standard platinum-based chemotherapy is safe for people with colorectal, esophageal, or ovarian cancers. The 13 participants received escalating doses of indomethacin alongside their ch…

This study compared two surgical approaches for early-stage cervical cancer: laparoscopic-assisted (minimally invasive) and open abdominal hysterectomy. Sixty women with stage IA1 to IB1 cervical cancer were randomly assigned to one of the two surgeries. Researchers measured surg…

This study compared two common antibiotics—azithromycin (single dose) and doxycycline (7-day course)—for treating anal chlamydia in women who also had a vaginal chlamydia infection. The goal was to see which treatment clears the anal infection better, since anal chlamydia often g…

This early-stage trial tested a new drug called PF-07257876 in 29 people with advanced lung, head/neck, or ovarian cancers that had stopped responding to other treatments. The drug is a bispecific antibody designed to help the immune system attack cancer cells. The main goals wer…

This large Phase III trial tested whether adding the drug bevacizumab to chemotherapy works better when the chemo is given into a vein (IV) or directly into the belly (IP). It involved 1560 people with advanced ovarian, fallopian tube, or peritoneal cancers. The goal was to see w…

This study tested a two-part vaccine (Ad26.Mos4.HIV and MVA-BN-HIV) combined with three broadly neutralizing antibodies (PGT121, PGDM1400, VRC07-523LS) in 28 adults with HIV who were already on suppressive antiretroviral therapy (ART). The goal was to see if this combination coul…

This study tested a new drug called XTX202 in 95 people with advanced solid tumors that had not responded to standard treatments. The goal was to check safety, find the right dose, and see if the drug could shrink tumors. The trial is now complete.

This study tested whether taking a probiotic called Lactobacillus crispatus LCr86 by mouth could improve vaginal health in women with an intermediate vaginal microbiome. 80 women participated, taking either the probiotic or a placebo for 8 weeks. Researchers measured changes in v…

This study tested a new technique to help women with primary ovarian insufficiency (early ovarian failure) become pregnant. Doctors removed one ovary, treated small pieces of it with drugs to wake up dormant eggs, and then transplanted the tissue back into the patient. After moni…

This study looked at whether adding a drug called epirubicin to the standard two-drug chemotherapy (paclitaxel and carboplatin) helps people with advanced endometrial cancer. Sixty patients were enrolled to see if the three-drug combo is better at controlling the disease before s…

This phase 2 trial tested whether the immunotherapy drug pembrolizumab (Keytruda) could help keep cancer from growing in people with platinum-resistant ovarian, fallopian tube, or peritoneal cancer. After initial chemotherapy with paclitaxel, 20 participants received pembrolizuma…

This study tested whether filling the bladder with a blue dye before surgery helps surgeons avoid accidentally injuring the bladder or ureters during a cesarean hysterectomy for placenta accreta. Sixty women were randomly assigned to receive the dye or standard care. The goal was…

This study tested an experimental drug called CBX-12 in 69 adults with advanced solid tumors (like ovarian, lung, breast, or colon cancer) that had stopped responding to standard therapies. The main goals were to check the drug's safety, find the best dose, and see if it could sh…

This study looked at the long-term safety of the cancer drug vismodegib in 19 patients with ovarian cancer, basal cell carcinoma, or metastatic colorectal cancer. All participants had previously taken vismodegib in an earlier Genentech trial and were expected to benefit from cont…

This phase II trial tested whether combining two drugs, pembrolizumab and olaparib, could help people with persistent or recurrent endometrial cancer or carcinosarcoma. The study enrolled 26 participants and looked at how many responded to treatment and what side effects occurred…

This study tested a special gel called Juveena in 150 women who had certain gynecologic procedures that put them at high risk for developing scar tissue inside the uterus. The gel is placed into the uterus right after the procedure to see if it can safely reduce the formation and…

This phase 3 trial tested whether adding the immunotherapy drug atezolizumab to standard chemotherapy and bevacizumab helps women with advanced, persistent, or recurrent cervical cancer live longer. The study enrolled 410 participants and compared the new combination against the …

This early-phase trial tested a new treatment called Radspherin for women with ovarian cancer that has returned and spread in the abdomen. Radspherin consists of tiny radioactive particles injected directly into the belly after surgery to remove visible tumors. The study involved…

This study tested a new experimental treatment called HPVST cells in 32 people with HPV-related cancers that had returned or not responded to standard care. The cells are grown from the patient's own blood and trained to attack HPV-infected cancer cells. The goal was to find a sa…

This study looked at whether a fast blood test (ROTEM) done during surgery for placenta accreta can help doctors decide when to give blood transfusions. 32 women took part, with half getting the rapid test and half getting standard lab tests. The goal was to see if the rapid test…

This study looked at 99 IVF patients with endometriosis (a condition where uterine-like tissue grows elsewhere) and a positive BCL6 test. It compared a cheap oral pill (norethindrone acetate) to an expensive injection (Depo Lupron) given before embryo transfer. The goal was to se…

This Phase 3 trial tested whether taking the drug selinexor as a maintenance pill after chemotherapy can help delay cancer progression in people with advanced or recurrent endometrial cancer. 263 participants who had responded to initial chemo were randomly assigned to receive ei…

This study tested whether Erzhi Tiangui granules, a traditional Chinese herbal blend, could improve live birth rates in women aged 35 to 43 with poor ovarian response undergoing IVF. The trial involved 480 participants across multiple centers and compared the herbal granules to a…

This study tested the safety of using pHyph, a vaginal tablet that naturally restores acidity, for 12 days in 32 adult women with bacterial vaginosis (BV). BV is a common infection causing unpleasant discharge and odor, and often returns after antibiotic treatment. The goal was t…

This phase 2 trial tested a combination of three drugs—rucaparib, bevacizumab, and atezolizumab—in 30 people with recurrent or progressive endometrial cancer that had not responded to prior treatments. The goal was to see if the combination could shrink tumors or slow the cancer'…

This study tested a handmade frameless IUD that releases the hormone levonorgestrel in 15 women at high risk of IUD expulsion due to conditions like adenomyosis or heavy bleeding. The device was made by combining an anchor system with a standard IUD after removing its T-shaped ar…

This study tested two ways to help women with cervical dysplasia stop smoking: nicotine patches, gum, or lozenges versus electronic cigarettes. Thirty-one women participated for six weeks. The goal was to see if these methods are acceptable and help reduce or stop smoking. It was…

This phase 3 trial tested whether a surgical procedure called laparotomy plus heated chemotherapy (HIPEC) could improve outcomes for colorectal cancer patients at high risk of cancer spreading in the abdomen. 150 patients who had already undergone surgery and chemotherapy were ra…

This study tested a new drug called STRO-002 in 19 Chinese adults with advanced ovarian, endometrial, or other solid tumors that had not responded to prior treatments. STRO-002 is an antibody-drug conjugate, meaning it combines a targeted antibody with a chemotherapy drug to deli…

This phase 2 trial tests the drug utidelone in 126 people with advanced solid tumors (excluding breast, lung, and colorectal cancers) that have not responded to standard treatments. The study aims to see if the drug can shrink tumors and how safe it is. Participants receive utide…

This phase 2 trial tested whether adding the immunotherapy drug atezolizumab to standard chemoradiation helps people with locally advanced cervical cancer. 189 participants received either the combination or standard treatment alone. The goal was to see if the combination delays …

This study tested whether taking low-dose aspirin (150 mg) daily, starting in the first trimester, could reduce pregnancy complications in women with type 1 or type 2 diabetes. The trial included 137 women and looked at outcomes like preeclampsia, early preterm birth, low birth w…

This phase II trial tested whether adding metformin, a common diabetes drug, to standard chemotherapy could help control advanced ovarian, fallopian tube, or primary peritoneal cancer. 111 participants received either metformin or a placebo alongside chemotherapy, followed by mai…

This study tested whether the drug rucaparib can help keep metastatic or recurrent endometrial cancer from growing. 79 women who had already received chemotherapy took either rucaparib or a placebo pill twice daily. The goal was to see if rucaparib could delay cancer progression …

This study tested a new dual laser treatment for vulvar lichen sclerosus, a chronic skin condition causing discomfort. 66 participants were randomly assigned to receive either laser therapy or standard steroid cream. The goal was to see if the laser works as well as the cream, po…

This early-stage study tested a new drug called DF6215, alone or with another drug (pembrolizumab), in 35 adults with advanced solid tumors that could not be removed by surgery or had spread. The main goals were to find the safest dose and check for side effects. The study is com…

This study tests a new drug called ZN-c3 (azenosertib), either alone or combined with niraparib, in 117 women with ovarian cancer that no longer responds to platinum chemotherapy. The goal is to find safe doses and see if the drugs can shrink tumors. It is an early-stage trial, s…

This early-phase study tested a new drug called ZN-c3 (Azenosertib) in 274 adults with various solid tumors. The main goals were to find a safe dose and check for side effects. Researchers also looked for signs that the drug could shrink tumors. This is a first step to see if the…

This study tested a combination of two drugs, lenvatinib and pembrolizumab, against standard chemotherapy in 827 people with advanced endometrial cancer that had worsened after initial treatment. The goal was to see if the combo could delay cancer growth and extend life. Results …

This study tested an experimental drug called ZN-c3 (azenosertib) in 92 women with a rare and aggressive type of uterine cancer that had come back or not responded to standard treatments. The goal was to see if the drug could shrink tumors and to check its safety. The drug is tak…

This phase 2 study tested a combination of two drugs, fulvestrant and abemaciclib, in 28 patients with a specific type of uterine cancer that is sensitive to hormones. The goal was to see if the drugs could shrink tumors or stop them from growing. Researchers also tracked side ef…

This study looked at 53 adults with advanced soft tissue sarcoma who had stable disease or improvement after 6 cycles of trabectedin. Half continued the drug, while the other half took a break (drug holiday). The goal was to see which approach better delays cancer progression and…

This study tested whether adding a diabetes drug (polyethylene glycol loxenatide) to a hormone-releasing IUD (LNG-IUS) helps women with a precancerous uterine condition called endometrial atypical hyperplasia. The 30 participants were all obese and wanted to preserve their fertil…

This study tested a new drug combination (tiragolumab plus atezolizumab) against atezolizumab alone in 172 people with advanced or returning cervical cancer that has a specific marker (PD-L1-positive). The goal was to see if the combination could shrink tumors better. Participant…

This study compared two approaches for inducing abortion in the second trimester for women who have a scarred uterus (e.g., from a previous C-section). One group received a laminaria tent (a seaweed rod that gently opens the cervix) for 12 hours followed by misoprostol pills, whi…

This study looked at 846 women doing their first IVF cycle to compare two drug mixes: follitropin delta plus menotropin versus follitropin alfa plus menotropin. The goal was to see which combination leads to more usable embryos and lower costs. Results help doctors choose the mos…

This study tested a combination of two drugs, pamiparib and surufatinib, in 29 women with ovarian cancer that stopped responding to platinum chemotherapy and had previously taken PARP inhibitors. The goal was to see if the combo could control the cancer for at least 6 months. The…

This study tested a combination of two drugs—NT-I7 (efineptakin alfa) and pembrolizumab (Keytruda)—in 215 people with advanced solid tumors that had stopped responding to treatment. The goal was to check safety, find the right dose, and see if the combo could shrink tumors. The t…

This study tested a combination of an immunotherapy drug (anti-PD-1) and a chemotherapy drug (albumin-bound paclitaxel) in 27 people whose cervical cancer had returned or worsened after standard treatment. The goal was to see if the combination could shrink tumors and help patien…

This study tested a combination of two drugs, apatinib and etoposide, in 35 women with ovarian cancer that had stopped responding to platinum-based chemotherapy. The goal was to see if the combination could shrink tumors or slow disease progression. Participants took the drugs by…

This study tested whether thumbtack needle acupuncture can improve ovarian function in 240 women aged 18-40 with diminished ovarian reserve (low egg supply). Participants received acupuncture at specific points for up to 4 weeks. The main goals were to see changes in anti-Mülleri…

This early-phase trial tested a new drug called BGB-10188, alone or combined with other cancer drugs (zanubrutinib for blood cancers, tislelizumab for solid tumors), in 97 patients whose cancers had returned or stopped responding to treatment. The main goals were to find safe dos…

This study tested whether vaginal capsules containing live lactobacilli (good bacteria) are safe and tolerable for treating bacterial vaginosis (BV), a common infection. Fifty-seven women with BV took either the lactobacillus capsules or the standard antibiotic metronidazole. The…

This study tested whether vaginal probiotic capsules can cure bacterial vaginosis (BV) better than a placebo. 402 women with BV took part. The main goal was to see if more women were cured 21-30 days after treatment with the probiotic compared to placebo. The trial was completed …

This study tested a new oral medication, oteseconazole, to see if it can prevent recurrent yeast infections in women who have had at least three infections in the past year. Over 400 participants took either the study drug or a placebo for 12 weeks after an initial treatment, and…

This study tested whether vaginal capsules containing two types of Lactobacillus probiotics can treat bacterial vaginosis, a common vaginal infection. Sixty-six women received either the probiotic capsule or a placebo. The goal was to see if the probiotics could restore normal va…

This study tested a new oral medication, oteseconazole, to see if it can prevent recurrent yeast infections in women who have had at least three infections in the past year. Participants first received standard treatment for their current infection, then took either oteseconazole…

This study tested a device that uses UVA and blue light to treat bacterial vaginosis and yeast infections. 38 women received one or two light treatments. Researchers checked if symptoms improved and if the vaginal microbiome became healthier. The goal is to find an alternative to…

This study looked at whether using an anti-cancer cream (5-fluorouracil) in the vagina after surgery is an acceptable and feasible way to treat cervical precancer in 180 South African women living with HIV. The goal was to see if women would stick with the treatment and find it a…

This completed Phase 3 trial compared two fertility drugs—follitropin delta (Rekovelle) and follitropin alfa (Gonal-F)—in 301 Chinese women undergoing IVF. The goal was to see which starting dose leads to the best number of eggs retrieved. Participants received daily injections f…

This study looked at whether adding vaginal estradiol or oral guaifenesin to standard fertility treatment (clomiphene citrate) could improve pregnancy rates. 90 women with infertility were randomly assigned to one of three groups. The goal was to see if these add-ons helped with …

This early-phase study tested whether adding a new drug called LDE225 to standard chemotherapy (paclitaxel) is safe for women with ovarian cancer that no longer responds to platinum-based treatments. Fifteen participants were monitored for side effects and to find the best dose. …

This study tested whether two natural supplements (acetyl L-carnitine and myo/chiro-inositol) can help women with PCOS ovulate and become pregnant. 120 women aged 18-35 with PCOS-related infertility took part. The goal was to see if these supplements improve ovulation and pregnan…

This study tested two antibiotics, azithromycin and erythromycin, in 250 pregnant women whose water broke too early (between 28 and 34 weeks). The goal was to see which drug better prevents infection in the mother and improves newborn health. Participants took one of the two anti…

This phase 3 trial tested whether a newer, more precise type of radiation (image-guided intensity modulated radiotherapy) could reduce long-term bowel problems compared to standard radiation in 300 women who had surgery for cervical cancer. The study focused on lowering severe bo…

This study tested a new drug called RP-6306 in 28 people with advanced cancer that could not be cured. The goal was to see if adding RP-6306 to standard treatment helps shrink tumors and is safe. Researchers also looked for specific biomarkers to see if some patients respond bett…

This early-stage trial tested a new oral drug, MSP008-22, in 7 adults with advanced solid tumors (breast, ovarian, prostate, head and neck cancers) that had spread or could not be removed. The main goal was to find a safe dose and check for side effects. This is a first step to s…

This study looked at how effective and safe niraparib is for Korean women with epithelial ovarian cancer. It included 850 patients who took niraparib as maintenance therapy or as a later treatment. Researchers measured how long patients lived without their cancer getting worse an…

This phase 3 study tested whether combining the immunotherapy pembrolizumab with the targeted therapy lenvatinib works better than standard chemotherapy for women with advanced or recurrent endometrial cancer. Over 800 participants received either the drug combo or chemo. The goa…

This phase 3 trial tested whether adding the immunotherapy drug pembrolizumab to standard chemotherapy helps women with advanced cervical cancer live longer and keep the disease from growing. Over 600 women with persistent, recurrent, or metastatic cervical cancer took part. The …

This study looked at whether a special care plan led by a geriatrician and a nurse could improve survival and quality of life for older adults (70+) with advanced cancer. 792 patients with breast, colorectal, lung, prostate, bladder, ovarian cancer, or lymphoma took part. The app…

This early-phase trial tested a new drug called SNB-101 in 21 people with advanced solid tumors (like colorectal, breast, and lung cancers) that had stopped responding to standard treatments. SNB-101 is a nanoparticle version of SN-38, the active part of a common chemotherapy dru…

This early-phase trial tested an experimental drug called VS-6766, given alone or with everolimus, in 104 adults with advanced solid tumors or multiple myeloma that had stopped responding to standard treatments. The goal was to find a safe, tolerable dosing schedule and measure h…

This study looked at whether the HPV vaccine can help prevent high-grade cervical lesions (precancerous growths) in women living with HIV who were already being treated for HPV. About 536 women took part, receiving either the HPV vaccine or a placebo. The goal was to see if the v…

This study tested a new immunotherapy drug, ezabenlimab, combined with other cancer medicines in 211 adults with advanced solid tumors that had spread. The goal was to see if the tumors shrank or disappeared. Participants received different drug combinations, and doctors monitore…

This early-phase trial tested a new drug called CUE-102 in 42 adults with certain advanced cancers (colorectal, gastric, pancreatic, or ovarian) that had returned or spread despite prior treatments. The drug is designed to help the immune system attack cancer cells that carry a s…

This study looked at two ways to manage rectal endometriosis in women aged 35-50 who do not plan to get pregnant. One group received hormone therapy for 24 months, while the other had surgery followed by hormones. The goal was to see which approach leads to better digestive funct…

This early-phase trial tested a combination of two drugs—pembrolizumab (an immunotherapy) and nintedanib (a drug that blocks blood vessel growth)—in 196 adults with advanced solid tumors that had worsened after standard treatment. The main goal was to find the safest dose of nint…

This early-stage trial tested a new type of cell therapy for people with HPV-positive head & neck or cervical cancer. The treatment uses a patient's own immune cells, engineered to recognize and attack HPV-infected cancer cells. Some patients also received cells that produce an a…

This study tested two common antibiotics, clindamycin and metronidazole, taken orally for a week to treat abnormal vaginal flora in pregnant women at high risk for preterm labor. The goal was to see which drug better clears the infection and reduces risks like early delivery. 166…

This phase 2 trial tested a drug called mirvetuximab soravtansine in 79 people with recurrent platinum-sensitive ovarian, peritoneal, or fallopian tube cancers that have high levels of a protein called folate receptor-alpha. The drug is given by IV every three weeks. The main goa…

This study tested a new drug called RC88 in 43 women with ovarian, fallopian tube, or peritoneal cancer that stopped responding to platinum chemotherapy. The goal was to see if RC88 alone could shrink tumors and how safe it was. Participants had already tried at least three other…

This study followed 86 women under 40 with premature ovarian failure (early menopause) who had received a one-time gene therapy using their own stem cells. The goal was to check long-term safety and see if hormone levels and fertility improved over 2.5 years. No new treatment was…

This phase 2 trial tested the drug nirogacestat in 53 people with recurrent ovarian granulosa cell tumors, a rare type of ovarian cancer. The goal was to see if the drug could shrink tumors or slow the disease. Participants took nirogacestat orally, and researchers measured how m…

This early-stage study tested a new drug called BAT1308 in 59 people with advanced solid tumors that had stopped responding to standard treatments. The main goal was to find a safe dose and check for side effects. Researchers also looked at how the drug moves through the body. Th…

This trial tests whether a vaginal self-sampling device can accurately detect high-risk human papillomavirus (HPV) compared to samples collected by a clinician. About 1,000 women aged 30-64, either regular screening attendees or those who haven't been screened in 3+ years, will p…

This trial is testing whether 3D ultrasound can diagnose placenta accreta spectrum more accurately than the standard 2D ultrasound with color Doppler. Placenta accreta is a serious pregnancy condition where the placenta grows too deeply into the uterine wall, which can cause seve…

This study is testing whether a simple blood test can help doctors tell apart two main causes of intrauterine growth restriction (IUGR) — a condition where a baby grows slower than expected in the womb. The test measures the ratio of two proteins, sFlt-1 and PlGF, which are linke…

This study looks at which tests work best to find early signs of HPV-related cancer in the cervix or anus of people living with HIV. About 1,586 participants from Mexico and Puerto Rico will be tested using different methods, including HPV tests and cell samples. The goal is to c…

This trial tests whether a green dye, injected during keyhole surgery to remove benign ovarian cysts, can show how well the ovary is still getting blood flow. The idea is that better blood flow might mean the ovary is healthier and more likely to support a future pregnancy. Women…

This completed Phase 1 study tested a new radioactive imaging agent called [123I]I-DARPIN-Ec1 in 10 people with lung or ovarian cancer. The goal was to see how the agent spreads in the body and whether it can help spot tumors on SPECT scans. Researchers compared the new scan resu…

This study tests a special SPECT imaging agent that seeks out a protein called LRRC15, found on many aggressive cancers like pancreatic, breast, lung, and brain tumors. The goal is to see if this scan can help doctors diagnose and stage these cancers more accurately. Healthy volu…

This study tested whether a special MRI technique called susceptibility weighted imaging (SWI) can better detect endometriosis lesions before surgery. Endometriosis spots often contain old blood, which SWI is good at seeing. Researchers compared SWI-MRI findings with what surgeon…

This study looked at whether women would be willing to collect their own urine sample for cervical cancer screening instead of a traditional swab. 173 women aged 31-49 at a French hospital tried it and answered questions about their experience. The goal was to see how acceptable …

This study looked at whether measuring certain molecules in the blood (microRNAs) can accurately detect early-stage endometriosis. Researchers compared the blood test results to the standard surgical diagnosis in 60 women. The goal is to find a non-invasive way to diagnose endome…

This study tested a special pad (PadKit™) worn for 4-6 hours to collect cells shed from the uterus. Researchers wanted to see if the pad could gather enough cells to tell the difference between normal tissue, precancerous changes, and cancer. 80 women scheduled for surgery (some …

This study looked at whether PET scans can better detect endometriosis lesions before surgery compared to standard MRI and ultrasound. Fifteen women with symptomatic endometriosis scheduled for surgery received a PET scan, and the results were compared with what surgeons actually…

This study looked at whether fluid collected from behind the vagina (culdocentesis) can help diagnose ovarian cancer. Researchers measured tumor markers CA-125 and HE4 in the fluid of 52 women scheduled for surgery. They also checked a urine sample for estrogen ratios. The goal w…

This study tested whether a rapid point-of-care test (Xpert® Xpress MVP) helps doctors diagnose vaginal infections more accurately than usual methods. 351 women with symptoms like discharge or itching were randomly assigned to either usual care or the rapid test. Researchers then…

This study looked at 45 patients whose HPV tests came back negative but had a late signal in the raw data. Researchers wanted to see if these late signals might actually indicate early cervical cell changes. By comparing different lab methods, they aim to improve how we interpret…

This study compared two imaging methods for diagnosing female infertility: MRI with a contrast dye and traditional X-ray. The goal was to see if MRI, which uses no radiation, could provide a complete and accurate assessment. Forty women participated, and researchers measured how …

This study tested a new saliva-based test to diagnose endometriosis, a painful condition that often takes years to identify. Researchers collected saliva from over 1,100 women with confirmed or suspected endometriosis to see if the test could accurately detect the disease. The go…

This study tested a new way to screen for cervical cancer using samples women collect themselves at home. Researchers wanted to see if a test that looks at DNA changes in HPV could better identify who truly needs follow-up care. About 294 women participated, and the goal was to m…

This study looked at whether a substance in the blood called adropin can help identify placenta accreta spectrum, a serious condition where the placenta grows too deeply into the womb. Researchers measured adropin levels in 84 pregnant women—42 with the condition and 42 healthy—t…

This study aimed to find DNA markers in the blood that could help detect a serious type of ovarian cancer early. Researchers compared DNA from women with and without ovarian cancer to identify differences. The goal is to develop a simple blood test for earlier diagnosis. Ten wome…

This study tested a new imaging system that uses a fluorescent dye to help surgeons see cancer that has spread to the lining of the abdomen (peritoneum) during surgery. 18 adults with stomach, ovarian, or mesothelioma cancers that had spread to the abdomen were injected with the …

This completed study looked at whether certain molecules in the blood (kisspeptins and miRNAs) can help diagnose non-viable pregnancies, including ectopic pregnancies. Researchers collected blood samples from 433 women to measure these biomarkers. The goal is to develop a more ac…

This study in Addis Ababa, Ethiopia, tests whether giving protein supplements only to pregnant women who are undernourished can prevent problems like low birth weight and stillbirth. Over 6,700 pregnant women are randomly assigned to receive supplements either universally or only…

This study followed 40 women at high genetic risk for ovarian cancer due to BRCA mutations or strong family history. One group chose to have their ovaries and fallopian tubes removed to prevent cancer, while the other group opted for regular CA-125 blood tests every 3 months to c…

This study tests a program called 'Health is Wealth: A Cervical Health Program' designed to encourage cervical cancer screening among African American and Sub-Saharan African immigrant women. Participants attend a two-hour educational session and receive an HPV self-sampling kit …

This study tests whether limiting daily eating to an 8–10 hour window can improve metabolic health and potentially lower the risk of endometrial cancer. Overweight or obese Native Hawaiian/Pacific Islander women at elevated risk will follow a time-restricted eating schedule for s…

This study tested whether giving albumin and furosemide right after egg retrieval can prevent severe ovarian hyperstimulation syndrome (OHSS) in women at high risk during ICSI. OHSS can cause swelling, fluid buildup, and sometimes hospitalization. The trial involved 200 women and…

This study looked at whether giving the Gardasil 9 HPV vaccine to women at the same time as surgery for abnormal cervical cells (CIN) can help clear the virus and prevent future infections. About 1,100 women aged 18-55 took part. The goal was to see if the vaccine reduces the cha…

This study tested whether offering a vaginal self-sampling kit directly to women aged 50-65 who had not had a cervical smear in over three years would increase screening participation. Women received a kit to use at home and mail to a lab for HPV testing. The goal was to see how …

This study tested a two-step screening process to find postmenopausal women at higher risk for endometrial cancer. Those identified as high-risk received a hormone challenge test and, if positive, standard care plus a lifestyle program. The goal was to see if this approach is pra…

This completed trial enrolled 797 Asian American women (Korean, Vietnamese, Chinese) aged 30-65 who were overdue for cervical cancer screening. All participants received community education and help scheduling a clinic screening. Half also got an HPV self-sampling kit to use at h…

This study tested whether giving a low dose of esketamine during ovarian cancer surgery could prevent depressive symptoms that often follow. 568 women undergoing cytoreductive surgery received either esketamine or a placebo. Researchers measured depression using a standard questi…

This study tested a program called Babble Boot Camp for babies with classic galactosemia, a rare condition that often causes speech and language problems. The program started when babies were 2 to 24 months old and involved weekly online coaching for parents from a speech therapi…

This study tested a daily dietary supplement (DITTO Cycle Supplement) in 40 women aged 18-45 who regularly experience period symptoms like cramps, bloating, fatigue, and mood swings. Over three menstrual cycles, researchers tracked changes in symptom severity and quality of life …

This study tests whether a non-ablative radiofrequency treatment can improve vaginal tissue health and reduce symptoms of Genitourinary Syndrome of Menopause (GSM), such as dryness and discomfort, in postmenopausal women. Participants will be randomly assigned to receive either t…

This early-stage trial is testing whether a topical solution containing calcitriol, a form of vitamin D, can safely reduce hair loss in adults receiving taxane-based chemotherapy for breast, gynecologic, or other solid tumors. Participants apply the solution to their scalp twice …

This study tested a fractional carbon dioxide laser treatment for women with vaginal and urinary symptoms like dryness, burning, pain during sex, and incontinence. One hundred women received three laser sessions about six weeks apart. The main goal was to see if symptoms improved…

This trial tests whether a 12-week structured physiotherapy program—including stretching, aerobic jogging, Kegel exercises, and relaxation—can reduce the severity of period pain in 360 female physical therapy students with primary dysmenorrhea. Participants are randomly assigned …

This study tests four different vaginal treatments (estrogen, DHEA, estrogen with probiotics, and a moisturizer) in 160 breast cancer patients who have vaginal atrophy due to hormone therapy. The goal is to see which treatment best relieves symptoms like dryness and pain, and imp…

This trial tests whether combining breathing exercises with core stabilization exercises relieves menstrual pain better than core exercises alone. It enrolls 48 women aged 18–25 with primary dysmenorrhea, who will attend supervised sessions three times a week for eight weeks. Res…

This study tests a psychosocial program called Conquer Fear Support (CFS) for people with stage III or IV lung or gynecologic cancer who are experiencing fear of cancer progression. The program includes psychoeducation, attention training, worry management, and detached mindfulne…

This trial tests whether an ultrasound-guided erector spinae plane block can reduce pain and the need for opioids during and after cesarean sections in women with placenta accreta, a condition where the placenta grows too deeply into the uterine wall. Participants will receive th…

This study looks at whether a program called prehabilitation—which helps patients get stronger and healthier before surgery—can lower the chance of problems after surgery for advanced ovarian cancer. About 146 women having surgery for ovarian cancer will take part. The goal is to…

This study tested whether a TENS unit, a small device that sends mild electrical pulses through the skin, can reduce pain during endometriosis flares. Forty women with surgically confirmed endometriosis tracked their pain for three months without the device, then for three months…

This trial tests whether drinking lavender herbal tea twice daily for nine days around each menstrual cycle can reduce the emotional and physical symptoms of premenstrual syndrome (PMS), such as anxiety, depression, stress, and pain. Sixty women with PMS will be randomly assigned…

This trial investigates whether adding electroacupuncture to a daily nutritional supplement can reduce the severity of premenstrual syndrome (PMS) in young women aged 20 to 29. Participants receive either the supplement alone or the supplement plus 21 sessions of electroacupunctu…

This pilot study tests if a gentle massage technique called manual lymphatic drainage (MLD) can reduce period pain in young women aged 18-25 with primary dysmenorrhea. Twenty participants will receive three monthly MLD sessions before their period. Researchers will measure pain, …

This trial investigates whether a 20-minute warm-water footbath containing magnesium sulfate can reduce pain in women with primary dysmenorrhea (painful periods). Around 120 women aged 18–35 are randomly assigned to receive the magnesium footbath, a plain warm-water footbath, or …

This study is testing whether a daily cream (7-0940®) can safely improve symptoms of vaginal atrophy in 10 women who have already completed laser therapy. Researchers will check vaginal health, quality of life, and any side effects over 45 days. The goal is to see if the cream he…

This study tested a 4-week exercise program before surgery (prehabilitation) in 34 women with cervical cancer. The program included aerobic, resistance, and pelvic floor exercises. Results suggest it may improve pelvic floor strength and shorten hospital stays compared to standar…

This study tests whether coloring mandalas or listening to classical music can reduce premenstrual syndrome (PMS) symptoms and improve quality of life. 108 female students with PMS will be split into three groups: mandala coloring, music listening, or no intervention. The trial i…

This study tested whether bupropion, a medication that affects brain chemicals, can improve low sexual desire in women who have had breast or gynecologic cancer. About 230 women took either bupropion or a placebo pill for 9 weeks. The main goal was to see if their self-reported s…

This study tested a web-based program to improve quality of life and reduce stress in ovarian cancer survivors. 326 women participated, comparing a mindfulness program to a healthy lifestyle program. The goal was to see if the online programs could help with stress, anxiety, mood…

This study investigates whether performing progressive muscle relaxation exercises before an endometrial biopsy can help reduce pain, lower anxiety, and improve comfort in premenopausal women. Participants will be women aged 40 or older with irregular cycles who need this biopsy.…

This study looked at whether SuJok therapy—a technique that applies pressure to specific points on the hands and feet—can reduce period pain and improve quality of life in young women with primary dysmenorrhea (painful periods without an underlying medical cause). Researchers enr…

This study tests whether a non-invasive device that gently stimulates a nerve in the ear can reduce menstrual pain, depression, and anxiety in young women with primary dysmenorrhea (painful periods without an underlying condition). Participants receive either real or sham stimula…

This study investigates whether an extract from snakehead fish (Ophiocephalus striatus) can reduce menstrual pain in teenage girls with primary dysmenorrhea—cramps without an underlying disease. The trial gives participants either the fish extract or a placebo for 14 days before …

This study tested a drug called M701, given directly into the belly, combined with standard cancer therapy, for people with malignant ascites (fluid buildup) from stomach, colon, or ovarian cancer. The goal was to see if M701 could delay the need for fluid drainage and improve su…

This study tests whether high-intensity laser therapy (HILT) can reduce pain during intercourse for women with provoked vestibulodynia, a condition causing severe pain at the vaginal opening. About 145 women with moderate to severe pain will receive either real or sham laser trea…

This trial investigates whether daily seed cycling capsules can reduce common PMS symptoms like cramps, bloating, fatigue, and mood swings. Forty women aged 18 to 45 with a history of menstrual symptoms will take the capsules for two menstrual cycles and report changes through qu…

This study tested whether a food supplement can reduce the discomfort of premenstrual syndrome (PMS) in 110 healthy women aged 18 to 45 with mild to moderate symptoms. Half took the supplement and half took a placebo for three menstrual cycles. Researchers tracked symptom severit…

This study tests whether a podcast-based education program can reduce the severity of premenstrual syndrome (PMS) symptoms and improve quality of life in female university students. Participants listen to eight podcast episodes over four weeks that cover topics like understanding…

This trial tests whether a shorter-acting spinal anesthetic (prilocaine) helps pregnant women recover feeling and movement faster after a cervical stitch procedure compared to the standard drug (bupivacaine). About 129 healthy pregnant women at risk of preterm loss will receive o…

This study looked at whether watching a video through virtual reality goggles with music can reduce pain and improve sleep quality in women with period pain (dysmenorrhea). 77 women aged 15-49 with moderate to severe pain used either VR with music or just music alone for 3 days. …

This study tested whether auricular acupressure (pressing points on the ear) can reduce symptoms of premenstrual syndrome (PMS) in female college students. 66 participants received either real or sham acupressure over 8 weeks. Researchers measured changes in PMS symptoms and qual…

This study tested whether pelvic floor muscle training combined with patient education can improve genital and urinary symptoms in postmenopausal women. Fifty women participated in an 8-week program that included progressive exercises and information sessions. Researchers measure…

This study tested a small pellet placed under the skin that slowly releases a hormone called gestrinone to treat pelvic pain caused by endometriosis. About 100 women with confirmed endometriosis and ongoing pain after surgery took part. The goal was to see if the pellet is safe a…

This study tested whether a special nursing plan (called ERAS) could help women recover after surgery for cervical cancer. 160 women were split into two groups: one got the ERAS nursing plan, the other got standard care. The goal was to see if the ERAS plan could lower the risk o…

This study tested three behavioral approaches—sleep restriction, stimulus control, and systematic light exposure—to help gynecologic cancer survivors who have trouble sleeping. 78 participants completed the program, and researchers measured changes in sleep quality and daytime im…

This study tested whether combining motor imagery (mentally practicing movements) with gentle exercise can reduce menstrual pain and improve coordination. Forty-eight women with moderate to severe period pain were split into three groups: one did motor imagery plus exercise, one …

This study tested whether laughter yoga and sleep hygiene training could help university students with premenstrual syndrome (PMS). 45 female students took part in 4 weekly 45-minute laughter yoga sessions plus sleep hygiene advice. Researchers measured changes in PMS symptoms, s…

This study tested whether a structured cognitive behavioral therapy (CBT) program could reduce psychological distress and improve problem-solving skills in women with vaginismus. Sixty women were randomly assigned to either CBT sessions over three months or routine care. The resu…

This study looked at whether a one-hour hypnosis session, done 5 to 15 days before a hysterectomy for pelvic gynecological cancer, could lower anxiety around the time of surgery. Twenty-nine women participated, and the hypnosis was guided by a trained nurse. The main goal was to …

This study looked at whether acupuncture can reduce pain and improve daily life for women with painful periods (primary dysmenorrhea). 64 women aged 18-35 with regular cycles and moderate to severe pain took part. Researchers measured pain levels and quality of life before and af…

This study tested a new medication called OG-6219 in 354 women aged 18 to 49 with moderate to severe endometriosis-related pain. The goal was to see if three different doses could safely reduce pelvic pain compared to a placebo. The trial is complete, and results will show how we…

This study tested whether spinal stabilization exercises could help women with painful periods. Fifty women aged 18-30 with regular cycles and no childbirth history were split into two groups: one did the exercises, the other did not. Researchers measured pain, symptoms, and dail…

This study tested a 3-month treatment with a combination of vitamin D, green tea extract (EGCG), vitamin B6, and D-Chiro-inositol in 108 women with uterine fibroids who were planning surgery. The goal was to see if the supplement could ease symptoms and possibly help some women a…

This study looked at whether lifestyle changes can help reduce period pain in obese women aged 18 to 25. 67 women with moderate to severe pain took part. Researchers measured pain levels, severity, and other factors before and after the program.

This study tested a 3-month online program called PelvicSense to see if it helps reduce pain and improve sexual well-being in people with endometriosis. Twelve adults with a formal diagnosis took part entirely from home. Researchers measured pain intensity and other factors befor…

This completed study tested whether a special pain monitor (NOL index) could help doctors give the right amount of pain medication during laparoscopic endometriosis surgery. The goal was to reduce total painkiller use and improve recovery. The study included 125 premenopausal wom…

This study tested whether a special perineal massage technique could reduce pain during sex and vaginal tightness in women treated for gynecological cancer. 35 women received either the massage or standard dilator treatment over ten sessions. The goal was to see if the massage im…

This study looked at whether using a vaginal dilator for 12 weeks helps women who had brachytherapy for cervical cancer. Researchers measured sexual function, self-compassion, and quality of life in 80 participants at three time points. The goal was to see if this simple tool can…

This study looked at 120 women having open surgery for uterine fibroids to see which method best reduces bleeding. Doctors compared using a tourniquet, clamping the uterine artery, or no compression at all. The goal is to find the safest way to control blood loss and improve reco…

This study tested whether a simple mindfulness exercise—noticing natural changes in mood and body throughout the day—could improve wellbeing for couples dealing with infertility. 70 patients and their partners took part. The goal was to see if this low-cost, easy-to-learn approac…

This study tested two pelvic floor muscle strengthening methods—EMG-biofeedback and rebound therapy (gentle bouncing)—in 42 women with endometriosis. The goal was to see which better reduces pain, improves muscle strength, and boosts quality of life. Participants had moderate to …

This study tested whether regular footbaths during the luteal phase (the week or two before a period) could help women with premenstrual syndrome (PMS). 92 women participated, with one group receiving footbath therapy and the other receiving no treatment. Researchers measured sym…

This study looked at whether kinesio taping (a special elastic tape placed on the skin) can quickly ease period pain and related symptoms like trouble sleeping and fear of moving. Researchers compared real taping to a fake (sham) taping in 24 women aged 18-24 with primary dysmeno…

This study tested the safety and effectiveness of the DEXTER robotic system in 52 patients having a hysterectomy (removal of the uterus) and related surgery for non-cancerous conditions. The main goals were to see if the robotic procedure could be completed without switching to o…

This study looked at whether teaching college women about nutrition could reduce the severity of premenstrual syndrome (PMS). 210 female students aged 18-30 with mild to severe PMS took part. Researchers measured changes in PMS symptoms, stress levels, and physical activity after…

This study looked at whether spinal manipulation combined with connective tissue massage can reduce pain, menstrual symptoms, depression, and sleep problems in women with primary dysmenorrhea (painful periods). Seventy-five women were split into three groups: one received both tr…

This study compared progressive relaxation exercises (tensing and relaxing muscles while breathing) with isometric exercises (holding muscle contractions) for managing period pain. Sixty women with moderate to severe primary dysmenorrhea took part. Researchers measured pain, othe…

This study tested whether a simple walking program, guided by a fitness tracker, could help cancer patients tolerate their chemoradiotherapy without missing treatments. 166 adults with brain, head and neck, lung, gastrointestinal, or cervical cancer participated. Patients were gi…

This study looked at whether following a healthy diet based on the Alternative Healthy Eating Index (AHEI) for 12 weeks could reduce pain and improve quality of life in women with endometriosis. 109 women with confirmed endometriosis and significant pain took part. Researchers me…

This pilot study tested a portable TENS device for reducing menstrual pain in 34 women with primary dysmenorrhea. Participants used the device on their lower abdomen during pain episodes for up to three cycles. The goal was to see if this drug-free approach could ease pain and im…

This study tested whether an online exercise and education program could help cancer patients and survivors feel better during the COVID-19 pandemic. Thirty adults with metastatic breast or gynecological cancer, or breast cancer survivors, took part. The program aimed to reduce f…

This pilot study tested whether giving two medications (mifepristone and misoprostol) at the same time helps women deliver faster after a nonviable second-trimester pregnancy, compared to misoprostol alone. Thirty women between 14 and 28 weeks pregnant who needed labor induction …

This study tested a new way to follow up with gynecologic cancer survivors. Instead of seeing a doctor every time, patients saw a nurse at every other visit and used a smartphone app to help manage their health. The goal was to see if this approach improved self-management skills…

This study tested whether giving a steroid (dexamethasone) before inducing labor can help women deliver faster after their water breaks. Sixty first-time mothers with full-term pregnancies and ruptured membranes received either the steroid or a placebo. Researchers measured the t…

This study tested whether teaching women in menopause about good sleep habits (sleep hygiene) could improve their sleep quality and reduce common menopause symptoms like hot flashes and mood changes. Seventy women who had not had a period for at least a year took part. They recei…

This small pilot study looked at whether acupuncture given twice before surgery could help stabilize blood pressure in women having their uterus removed (total laparoscopic hysterectomy) for fibroids. Thirty-five adult patients received acupuncture before the operation, and resea…

This study developed and tested a smartphone app to help Taiwanese women with gynecological cancer learn about their condition and manage symptoms. 67 women used the app, which included a chatbot and educational content. Researchers measured changes in symptom distress, informati…

This study tested a home-based cognitive training program called BrainHQ in 60 women with gynecologic cancers who had memory or thinking problems after chemotherapy. Participants used the app for about 2.5 hours per week for 10 weeks. The goal was to see if the program was practi…

This study looked at whether a 10-week pelvic physical therapy program is practical for gynecologic cancer survivors who have sexual problems. Twenty survivors were enrolled to see if they could stick with the program and if it improved their sexual function and quality of life. …

This study tested two treatments for vestibulodynia, a chronic pain condition affecting the vulvar area. 209 women received either a lidocaine/estradiol cream, the antidepressant nortriptyline, both, or a placebo. The goal was to see which approach best reduces pain and improves …

This study tested two non-drug approaches for severe period pain: placing a dried Rose of Jericho plant in water near the person, and practicing 4-7-8 breathing exercises. 100 women aged 18-35 with very painful periods took part over three cycles. Researchers measured changes in …

This study tested whether adding ketoprofen to standard paracetamol (acetaminophen) can better control pain in patients receiving brachytherapy for cervical or upper airway/digestive tract cancers. Sixty-eight adults were randomly assigned to receive either paracetamol alone or p…

This study looked at whether taking vitamin E together with the painkiller mefenamic acid works better than the painkiller alone for period cramps. Sixty women aged 15-35 with painful periods took either the combination or just the painkiller. Researchers measured pain levels to …

This study tested a program called BOLSTER, designed to give extra support to people with gynecologic or gastrointestinal cancers and their caregivers after a hospital stay. The goal was to see if the program was practical and well-liked. 121 adults with complex care needs took p…

This study tested whether using the Livi postcoital tampon three times in a row is safe for the vagina. Sixty sexually active women inserted and removed the device during one clinic visit. Doctors checked for any tissue damage or pain. The goal was to see if the device causes har…

This study tested a program called PEEPS for people with endometriosis-related pelvic pain. Over eight weekly sessions, participants learned about mindfulness, yoga, nutrition, and pain coping strategies, while getting support from peers and clinicians. The goal was to see if the…

This study tested whether squeezing a stress ball during a gynecologic exam reduces pain and anxiety. 141 women aged 18-35 who had a Pap smear were randomly assigned to use a stress ball or not. The goal was to see if this simple technique could improve the patient experience and…

This study tested whether a mobile app helps cancer patients undergoing chemotherapy or radiation therapy report their symptoms more effectively. Over 200 participants used the app to track side effects for 8 weeks. The goal was to see if the app improves how patients recognize a…

This study tested a stepped-care telehealth program for cancer survivors living in rural areas who experience anxiety, depression, or sleep problems. Participants received either low-intensity check-ins or high-intensity phone therapy with a licensed therapist, depending on sympt…

This study looked at whether doing barre and gym ball exercises could reduce pain and distress and improve quality of life in women with painful periods (primary dysmenorrhea). 42 women with moderate to severe period pain took part. They did 30-minute exercise sessions three time…

This study tested whether aerobic exercise or Aviva exercises better relieve menstrual cramps and improve sleep, daily activities, and quality of life. It involved 42 unmarried women aged 20-40 with moderate to severe period pain. Participants were split into two groups, each doi…

This completed study compared an 8-week online yoga program to a conventional exercise routine in 52 women with endometriosis. The goal was to see if yoga could better reduce pain and improve quality of life. Participants practiced meditation, breathing, and gentle poses, while t…

This study tested a program to help young couples cope with reproductive and sexual health problems after breast or gynecologic cancer. 158 survivors and their partners took part in a videoconference intervention. The goal was to reduce distress and improve communication about fe…

This study looked at whether giving a tiny, non-anesthetic dose of ketamine during surgery could lower pain sensitivity right after the operation. It involved 84 women having laparoscopic salpingectomy for ectopic pregnancy. Researchers measured pain sensitivity using a questionn…

This study tested a web-based program called My Pelvic Plan for people with chronic pelvic pain, including those with endometriosis. The program teaches pain education, cognitive and behavioral skills, acupressure, physical activity, and basic pelvic floor therapy. Researchers me…

This study tested a hyaluronic acid filler (BtH Intimate 2.0%) injected into the labia and pubic area of 40 women with mild to moderate vulvar atrophy. The goal was to restore volume, improve appearance, and ease symptoms. Participants were followed for 6 months after a single tr…

This study tested Korean manupuncture, a hand-based therapy, for reducing pain in women with endometriosis. 74 women were randomly assigned to receive either real or placebo sessions. The goal was to see if this gentle, non-drug approach could help manage pain that often doesn't …

This study reviewed medical records of 73 women who had trouble emptying their bladder after cervical cancer surgery. Researchers compared two different sets of acupuncture points to see which worked better. The goal was to reduce leftover urine in the bladder and ease belly disc…

This study tested whether a combination of slow, guided breathing (called cardiac coherence) and a hypnosis session could help women feel less anxious before breast or gynecologic cancer surgery. Fifty-three women participated, practicing the breathing technique several times a d…

This study looked at 70 women having robotic surgery for pelvic organ prolapse. It compared standard gas pressure (15 mmHg) to a slightly lower pressure (12 mmHg) during the operation. The main goal was to see if the lower pressure led to less pain right after surgery, without ma…

This study tested whether acupressure, a technique from Traditional Chinese Medicine, can ease fatigue in ovarian cancer survivors. 171 women who had completed primary cancer treatment were taught to apply pressure to specific points on their bodies daily for six weeks. The study…

This study tested whether a nerve block (stellate ganglion block) combined with standard anesthesia could help women with uterine fibroids sleep better and feel less anxious after laparoscopic surgery. 233 women aged 35-55 took part. Results aim to show if this approach reduces s…

This study compared two surgical techniques for removing the uterus (hysterectomy) due to non-cancerous conditions: the newer vNOTES method (done through the vagina) and standard laparoscopy (keyhole surgery). 145 women took part, and researchers tracked complications, pain, and …

This study tested whether a 12-week adapted physical activity program could improve health-related quality of life in 51 women with endometriosis in Martinique. The program included aerobic, strength, and flexibility exercises. Researchers measured changes using a standard endome…

This phase 2 trial tested whether the drug letrozole can reduce pain during ovarian stimulation in 60 women with endometriosis. Participants received either letrozole or a placebo daily, and researchers measured changes in pain scores. The goal is to find a way to make fertility …

This study looked at whether laughter yoga can improve quality of life and reduce symptoms of premenstrual syndrome (PMS) in young people aged 18 to 25. Seventy-five participants with regular periods took part. The approach combines breathing exercises, clapping, and playful game…

This study tested whether cabergoline, a drug already used for other conditions, can reduce chronic pain in women and teens with endometriosis. 129 participants took either cabergoline or a placebo for 6 months. The goal was to see if this non-hormonal approach could safely ease …

This study tested whether oliceridine, a newer painkiller, is as safe and effective as the standard drug sufentanil for putting patients to sleep before gynecologic laparoscopic surgery. 120 women with endometrial cancer took part. Researchers monitored blood pressure and heart r…

This study tested a new treatment for postmenopausal women with vaginal atrophy—a condition causing dryness, burning, and pain. Researchers combined CO₂ laser therapy with a collagen cream to see if it worked better than laser alone. Sixty women aged 35 to 75 took part, and the t…

This study tested whether putting lignocaine (a numbing medicine) inside the abdomen during gynecologic open surgery can reduce pain afterward. 112 women having surgery like hysterectomy or cystectomy took part. The goal was to see if this approach lowers pain scores and the need…

This study tested the Triple P parenting program for mothers of children aged 6-13 with ADHD. The program teaches strategies to reduce behavior problems and boost mothers' confidence. 67 mothers took part, with some receiving the program and others not. Researchers measured chang…

This study tested whether an 8-session online mindfulness program could reduce PMS symptoms, fear of childbirth, and improve psychological well-being in 126 women with PMS. Participants were randomly assigned to either the mindfulness group or a control group. The results will sh…

This study tested two ways to inject a cortisone medicine (triamcinolone acetonide) to treat genital lichen sclerosus, a skin condition causing itching, pain, and discomfort in women. Twenty women who did not improve with standard creams received injections either by a traditiona…

This study tested whether a non-invasive brain stimulation method called tDCS can help relieve chronic pelvic pain in women with endometriosis. Thirty women who were already on hormone therapy and had daily pain scores above 4 out of 10 took part. They received multiple tDCS sess…

This study tested whether doing Pilates online with a live instructor could help women with painful periods. Thirty-four women with primary dysmenorrhea took part in 16 supervised sessions over eight weeks. Researchers measured pain, other symptoms, and trunk muscle endurance to …

This study tested whether a home-based exercise program could help people with persistent neck pain after a car accident. 80 adults were split into two groups: one did guided neck exercises at home, the other received standard manual therapy in a clinic. After 8 weeks, researcher…

This study tested whether a daily probiotic (Lactobacillus crispatus M247) combined with vaginal laser therapy can improve vaginal health and reduce symptoms like dryness, itching, and pain in menopausal women with atrophic vulvovaginitis. 75 women were split into two groups: one…

This study compared two types of nerve blocks (TAP and TFP) to see which provides better pain relief after a hysterectomy. 77 women having the surgery received one of the blocks, and researchers measured their pain scores and how much opioid painkiller they needed. The goal was t…

This study tested a new vaginal probe that uses special lights to treat vaginal atrophy in 25 postmenopausal women who had not been helped by other treatments. The probe aims to reduce pain and dryness by stimulating natural tissue repair. The main goal was to check safety and se…

This pilot study tested whether taking a combination of EGCG (from green tea), vitamin D, and D-chiro-inositol for three months before hysteroscopic myomectomy improves surgical outcomes. 90 women with uterine fibroids were divided into two groups: one received the supplements be…

This study used advanced brain imaging (MRI and MEG) to look for differences in brain structure, chemistry, and activity between people with schizophrenia and healthy volunteers. Over 3,200 adults took part. The goal was to better understand the brain changes linked to schizophre…

This study investigates why some girls with Turner syndrome find it hard to make friends, read emotions, and control their feelings. Researchers will compare 35 girls with Turner syndrome to 35 girls with isolated growth hormone deficiency, all aged 7 to 16. Through puzzles, memo…

This study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to one of these two methods or to standard care. The goal was to se…

This completed study from the National Institute of Mental Health looked at over 1,500 women to better understand the symptoms of premenstrual syndrome (PMS) and a severe form called PMDD. Researchers used interviews, rating scales, and hormone tests to track mood and behavior ch…

This study looked at 78 women to understand why chronic pelvic pain happens in endometriosis. Researchers examined hormones, immune chemicals, and genes, and how nerves and muscles are involved. Participants included women with endometriosis and pain, those with pain but no endom…

This study looks at how often women develop intrauterine adhesions (scar tissue inside the uterus) after having fibroids removed through laparoscopic or open surgery. Researchers will check for adhesions using a small camera inserted into the uterus three months after surgery. Th…

This study tests whether a family-centered developmental care program, called NIDCAP, can improve brain and behavior outcomes in preterm infants born with severe intrauterine growth restriction. The intervention involves weekly observations of each infant's behavior, with persona…

This study examines whether placentas from pregnancies with intrauterine growth restriction (IUGR) have different levels of certain progesterone receptors compared to healthy pregnancies. Researchers will analyze placental tissue collected after delivery from 90 women. The goal i…

This study looks at proteins in the blood of women with ovarian, peritoneal, or fallopian tube cancer who are in remission. The goal is to find a protein pattern, or 'fingerprint,' that signals when the cancer might come back. Researchers followed 119 women with stage III or IV c…

This study investigates whether lymph nodes in the lower abdomen, called the inferior epigastric lymph node basin, might be an early stop for ovarian cancer spreading from the peritoneum. Researchers will biopsy these nodes in 20 patients undergoing surgery for ovarian peritoneal…

This study looks at women who have had one cesarean section and are now deciding how to give birth again: trying a vaginal delivery (TOLAC) or scheduling another C-section (ERCD). The goal is to compare the safety of both options for the baby and the mother. Researchers will foll…

Women who become pregnant after weight-loss (bariatric) surgery have a higher chance of delivering smaller-than-expected babies. This study tests whether tracking blood sugar fluctuations with a continuous glucose monitor during each trimester can help predict which babies will b…

This trial investigates whether women with endometriosis have different blood pressure, pain, and platelet responses compared to healthy women. Participants take aspirin or a placebo and undergo handgrip exercise, cold pressor tests, and blood draws. The goal is to understand how…

This completed study looked at tumor samples from 687 women with advanced high-grade serous ovarian cancer who were treated with chemotherapy. Researchers examined different types of immune cells in the tumors to see if they were linked to how well patients did. The goal was to b…

This study looks at how steep head-down position and two types of anesthesia (total IV vs. balanced) change eye pressure in women having robotic surgery for gynecologic cancer. Researchers will measure eye pressure in 40 participants to see which anesthesia method causes less pre…

This study looks at whether self-compassion—treating yourself with kindness during tough times—helps explain the link between PMS symptom severity and quality of life. Researchers will survey female nursing students aged 18 to 25 who have PMS, measuring their symptoms, self-compa…

This study looks at whether a woman's expectations before endometriosis surgery influence her pain, disability, and well-being afterward. Researchers follow about 300 women for a year, tracking their symptoms and psychological factors. The goal is to understand why some women sti…

This study looks at what factors increase the risk of a serious complication called anastomotic leakage after ovarian cancer surgery. Researchers will analyze data from 401 patients to build a prediction model. The goal is to help surgeons identify high-risk patients early and ta…

This study tests whether a structured face-to-face education program can improve women's knowledge about cervical cancer and their attitudes toward the HPV vaccine. One hundred women aged 18-49 in Turkey will be split into two groups: one receives the education, the other gets ro…

This study looks at two ways to examine the uterine cavity after women have had hysteroscopic surgery for conditions like polyps, fibroids, or a uterine septum. One method is a non-invasive 3D ultrasound; the other is an office hysteroscopy, which involves inserting a small camer…

This study tests a digital education program designed to help newly diagnosed women with gynecological cancer learn about egg freezing (oocyte cryopreservation). The program uses videos, images, WhatsApp, and online meetings to teach about fertility preservation options. Research…

This study follows 67 women with cervical cancer for one year after they finish radiation therapy. Researchers want to see how their quality of life, including physical and emotional well-being, changes over time. Participants fill out questionnaires about symptoms like fatigue, …

This study aims to find the genes involved in inherited reproductive disorders, such as delayed or early puberty and low hormone levels. Researchers will analyze genetic data from 600 participants with these conditions. The goal is to identify genetic variations that may explain …

This study looks at how proteins in the blood change in women with ovarian cancer as they go through standard treatment. Researchers collected blood samples before surgery, after surgery, and after chemotherapy to see if these protein shifts could give a fuller picture of how the…

This study examines whether two specific ultrasound measurements—the ratio of the transverse cerebellar diameter to abdominal circumference and the ratio of mid-thigh circumference to femur length—can more accurately estimate gestational age in both healthy and growth-restricted …

This study looks at how sleep length and quality may affect the success of in vitro fertilization (IVF) in women. Participants will wear a ring-shaped device that tracks sleep patterns before and after a frozen embryo transfer. The goal is to see if sleep parameters like total sl…

This study looks at how the womb lining heals after different types of womb-sparing surgery for placenta accreta, a serious pregnancy condition where the placenta grows too deeply into the womb wall. Researchers will use a small camera (hysteroscopy) three months after surgery to…

This study looked at how certain enzymes called matrix metalloproteinases (MMPs) and their inhibitors relate to human papillomavirus (HPV) in cervical dysplasia and cancer. Researchers collected tissue and cell samples from 216 women with different stages of cervical lesions. The…

This completed study looked at whether a simple blood test (liquid biopsy) can help track breast, ovarian, and endometrial cancers. Researchers analyzed circulating tumor cells in 150 women to see if these cells could predict the risk of cancer spreading or how well treatment wor…

This completed study looked at a new antibody called anti-SIRPα as a potential immunotherapy for liver cancer. Researchers used blood and tissue samples from 30 liver cancer patients to see how the antibody affects immune cells. The goal was to understand whether blocking the SIR…

This study looked at two ways to help breast and ovarian cancer survivors get genetic counseling: a mailed brochure or a phone call with a health coach. About 668 women took part. The goal was to see which method led more people to actually get genetic counseling or testing. The …

This study looks at whether a score called KELIM can predict how well ovarian cancer patients respond to maintenance treatment with PARP inhibitors after initial chemotherapy. Researchers will analyze data from 243 patients who took part in the PAOLA-1 trial. If KELIM proves usef…

This study tested whether a short video featuring cancer survivors and local leaders could encourage more people in rural Tamil Nadu to get screened for oral, breast, and cervical cancer. Over 1,200 adults aged 30-59 who had not been screened recently were randomly assigned to se…

This study looked at 294 women with deep endometriosis affecting the rectum. Researchers compared how patients felt after conservative surgery versus more radical bowel removal. The goal was to see which approach leads to fewer bowel and bladder problems and to find factors that …

This study tested whether injecting a fluorescent dye called indocyanine green (ICG) into the ureters helps surgeons see them more clearly during laparoscopic surgery for deep infiltrating endometriosis. 51 women with suspected or confirmed deep endometriosis took part. The goal …

This study looked at 40 women to see if a physical measurement called anogenital distance (AGD) and certain hormone levels differ between those with and without endometriosis. Researchers measured AGD and took blood and saliva samples before and after showing an empathy-inducing …

This study tested three types of messages to encourage genetic testing in 1,283 people at risk for hereditary breast and ovarian cancer. Participants received an electronic health record message, then a text message, then a doctor's reminder if needed. The goal was to see which a…

This study followed 40 women with cervical, uterine, or ovarian cancer to see how their relationship and sexual communication changed from diagnosis to 3 months after treatment. Participants filled out questionnaires about their sexual activity, desire, and discomfort. The goal w…

This study looked at 1,500 women with advanced ovarian, peritoneal, or fallopian tube cancer to see how genetic changes in their tumors relate to how the disease progresses. Researchers collected tumor samples and medical data to find links between DNA abnormalities and outcomes …

This study tested whether a nurse navigation program—including education, counseling, and WhatsApp follow-up—could encourage more women aged 30-65 to get screened for cervical cancer. 80 women who were not regularly screened took part. The program aimed to improve their understan…

This study looked at a protein called osteopontin in the blood of pregnant women whose water broke too early (PPROM). Researchers compared 71 women with early rupture to those with normal-term rupture to see if protein levels differ. The goal was to learn more about the biology b…

This study looked at whether measuring the stiffness of uterine fibroids can help predict how well they respond to a non-invasive treatment called MR-HIFU. Forty women with symptomatic fibroids were enrolled. The goal was to improve patient selection so that only those likely to …

This pilot study tested a new device that measures cervical stiffness in 21 pregnant women at high risk for preterm birth. The goal was to see if stiffness measurements could improve risk assessment beyond standard ultrasound checks. Researchers hope this could lead to better pre…

This study tested whether a two-hour, peer-led workshop with religious messages could encourage Muslim women in North East England and Scotland to get screened for breast, bowel, and cervical cancer. 169 women aged 25-74 who were not up-to-date with all eligible screenings took p…

This study collected ultrasound and MRI images from 100 women with endometriosis who were scheduled for surgery. The goal was to create a database that helps doctors better identify and stage the disease using these scans. Participants were aged 18-40, had a clinical diagnosis, a…

This study looked at how doctors in Russia treat a specific type of ovarian cancer called HRD-positive. Researchers collected information from 414 patients to understand what treatments they received and how they fared. The goal was to describe real-world practice, not to test a …

This study looked at 384 women having their first C-section to compare two methods of closing the uterus: one layer of stitches vs. two layers. The goal was to see which method leads to better scar healing and fewer problems like pain or irregular bleeding. Researchers used ultra…

This study followed up with 69 women who had pelvic pain for over 6 months to see if a special pain education class still helped them 5 years later. The women filled out questionnaires about their pain, daily life, and sexual function. The goal was to find out if the benefits of …

This study looked at whether a special PET/CT scan, done within two months after treatment, helps doctors make better decisions for patients with advanced cervical cancer. Researchers compared what doctors would decide without the scan versus with it. The study involved 40 patien…

This completed study examined levels of certain proteins and growth factors in the placentas of 48 women with placenta previa or placenta percreta during the third trimester. Researchers measured substances like decorin, laminin, and collagen in placental tissue and blood samples…

This study tested a digital health platform to help people with a hereditary risk of breast and ovarian cancer share their genetic test results with family members. Researchers worked with 128 participants in Switzerland and Korea to see if the tool reduced distress and improved …

This study looked back at 388 women with advanced ovarian, fallopian tube, or peritoneal cancer who were taking the drug niraparib as maintenance therapy. Researchers wanted to see how often serious side effects happened and how patients used the drug in real-life UK clinics. No …

This study looked at 30 women with PCOS who had trouble ovulating. Researchers measured a hormone called AMH while giving low doses of FSH to see if a drop in AMH happens when an egg follicle starts to grow. The goal was to better understand why ovulation fails in PCOS, not to te…

This study looked at 40 women with symptomatic uterine fibroids to understand why MR-guided focused ultrasound (HIFU) works better for some than others. Researchers used MRI and contrast-enhanced ultrasound to measure fibroid blood flow, stiffness, and other features before treat…

This study looked at whether a common vaginal yeast, Candida albicans, plays a role in endometriosis. Researchers compared 48 women with and without endometriosis to see if yeast overgrowth was more common in those with the disease. The goal was to better understand what causes e…

This study interviewed 12 women diagnosed with gynaecological cancers (ovarian, womb, cervical, vulval, or vaginal) to understand what made them seek help or delay. Researchers focused on embarrassment and other barriers to early doctor visits. The goal is to use these insights t…

This study looked at 60 women who had surgery for borderline or benign ovarian tumors. Researchers used questionnaires to measure anxiety, depression, body image, and sexual health. The goal was to understand the emotional and psychosexual impact of a borderline tumor diagnosis c…

This study tested whether a family history app can help doctors collect and use information about patients' family health risks. Over 600 adults aged 30-69 took part. The goal was to see if the app leads to better screening and genetic referrals for conditions like cancer, heart …

This study reviewed over 11,000 patients with advanced ovarian cancer to see if hospitals that follow ten specific quality standards for surgery have better outcomes. The research looked at how long patients lived without their cancer getting worse and overall survival. The goal …

This completed study looked at how often joint pain occurs in 71 people with ovarian, colorectal, or lung cancer who were taking the drug bevacizumab. Participants filled out a questionnaire about their joint pain over 6 months. The goal was to better understand this side effect.

This study looked at 60 women aged 35 to 60 who had a hysterectomy (removal of the uterus) through small cuts in the belly (laparoscopy). The goal was to compare two different methods of tying off the uterine arteries to see which one led to less blood loss during surgery. The re…

This study tested whether a flexible, personalized exercise program is practical for cancer patients receiving chemotherapy. Twenty-one adults with breast, ovarian, or colorectal cancer took part. The main goal was to see if patients would join, attend, and stick with the exercis…

This study tested different ways to teach physical activity-related health competence to nursing students in Bavaria. Over 300 students from 16 schools participated, with some schools using new teaching methods and others serving as controls. The goal was to see which approach be…

This study follows over 1,700 women who previously took part in a cervical cancer screening trial. Researchers want to see if testing for HPV alone is as safe and effective as combining it with a Pap smear over 10 years. Participants provide a cervical sample for both tests, and …

This study looked at 172 kidney transplant recipients who were on stable anti-rejection medication for at least 3 months. Researchers measured levels of a common, harmless virus (Torque Teno Virus) in their blood to see if it could predict serious infections or organ rejection. T…

This study used ultrasound to measure the thickness between the bladder and uterus (vesicouterin thickness) and check for a 'sliding sign' in 117 pregnant women at term. Half had at least one prior C-section, half did not. The goal was to see if ultrasound can detect adhesions th…

This study looked at how hormonal birth control might help manage inflammatory bowel disease (IBD) symptoms that get worse during a woman's period. Researchers surveyed 50 women with IBD to understand their preferences for birth control and whether they would join a future trial.…

This study tested a program designed to reduce stigma around cervical cancer and increase screening among women in Nepal. Researchers enrolled 310 married women aged 30-60 from one municipality. The program included educational videos and group discussions. The goal was to see if…

This study gathered information from 32 people with cytolytic vaginosis, a poorly understood condition. Researchers aimed to identify risk factors, common symptoms, and how to diagnose it. They also looked at whether baking soda vaginal washes are an effective treatment. The goal…

This study looked at whether following national guidelines for ovarian cancer surgery is cost-effective. Researchers measured the cost per quality-adjusted life year (QALY) over three years in 200 women with advanced ovarian cancer. The goal was to understand the economic impact …

This study tested whether it is practical to routinely check ovarian cancer tumors for BRCA gene mutations in the clinic. Researchers enrolled 200 patients with high-grade serous or endometrioid ovarian, fallopian tube, or primary peritoneal cancer. They used blood and tumor samp…

This study analyzed blood, urine, and tissue samples from 273 adults with brain or lung cancer who were receiving radiation therapy. The goal was to find biological markers that could predict which patients are more likely to develop serious side effects from radiation, such as l…

This study looked at 56 women with endometriosis to see if severe pain during sex is linked to a condition called central sensitization, where the nervous system becomes overly sensitive to pain. Researchers used pain-pressure tests and daily surveys over 6 weeks to measure pain …

This study looked back at 46 women who had a procedure called uterine artery embolization to treat fibroids. The goal was to see how often women later had a baby and what pregnancy complications occurred. The researchers reviewed medical records from one hospital in France to gat…

This study aimed to find the best way to diagnose excess hair growth (hirsutism) and hair loss in women with PCOS. Researchers studied 1330 women to determine the most accurate scoring method. The goal is to improve diagnosis and understanding of these common symptoms.

This study looked at 492 women after menopause to see how often signs of endometriosis show up on routine ultrasound exams. Researchers used a standard method to check for deep endometriosis and cysts. The goal was to learn more about this condition in older women, which is not w…

This study looked at whether using frozen embryos instead of fresh ones in IVF leads to more live births. 237 women took part, and researchers compared pregnancy rates and baby health. The goal was to see if freezing embryos helps the womb lining work better.

This study looked at 22 women with cervical cancer to see if having an empty bladder (using a catheter) or a full bladder (filled with 120cc of fluid) is better during a type of internal radiation called brachytherapy. The goal was to find which method lowers the radiation dose t…

This study measured a substance called preptin in the umbilical cord blood of 72 newborns. Researchers compared levels in babies with low or high birth weight to those with normal weight, and also looked at babies born to mothers with diabetes. The goal was to see if preptin leve…

This study looked at whether a blood test that measures immune response to CMV can predict infection risk in children who have received a heart, kidney, or liver transplant. Researchers tested blood samples from 161 children within the first year after transplant. The goal is to …

This study examined 33 preterm babies born before 30 weeks to mothers with preeclampsia. Researchers measured certain proteins in the mother's blood, umbilical cord blood, and amniotic fluid to see if they were linked to a lung condition called bronchopulmonary dysplasia (BPD). T…

This completed study used 2D and 3D ultrasound to measure uterine and endometrium volume in 648 women with PCOS or HPOD, two conditions that cause irregular periods. The goal was to see if these measurements could help tell the two disorders apart. The study did not test any trea…

This completed study looked at how ovulation disorders affect quality of life in nearly 1,000 women aged 18-45 with irregular periods. Participants filled out a 36-question survey covering physical, emotional, and social well-being. The goal was to compare two groups: those with …

This study reviewed medical records of 51 women with ovarian, fallopian tube, or peritoneal cancer who received the drug rucaparib in real-world clinics, not just in strict trials. Researchers looked at patient history, side effects, dosing, and how long the drug kept cancer from…

This pilot study looked at whether repeated FDG-PET/CT scans can help select patients and evaluate how well a special chemotherapy (PIPAC) works for cancer that has spread to the lining of the abdomen. 34 patients with various abdominal cancers were included. The goal was to see …

This study looked at 386 women with cervical, uterine, or ovarian cancer to compare standard laparoscopic surgery versus robot-assisted laparoscopic surgery. The goal was to see which approach causes fewer complications within six months after the operation. Researchers tracked s…

This study explores whether using a PET-scan at the start of brachytherapy (internal radiation) is feasible for patients with locally advanced cervical cancer. Fourteen participants who have already received chemoradiation will undergo an extra PET-scan during brachytherapy and a…

This study looked at whether monthly nutrition education workshops could improve eating habits and reduce premenstrual syndrome symptoms in 50 adolescent female soccer players aged 15-17. Over five months, the workshops covered sports nutrition topics. Researchers measured change…

This study looked at whether the level of thyroid-stimulating hormone (TSH) in the blood affects the success of a fertility treatment called ICSI. Researchers measured TSH in 180 women on day 2-3 of their menstrual cycle and then tracked egg retrieval, fertilization, and pregnanc…

This study looked at over 1,800 frozen embryo transfer cycles to see if a woman's body mass index (BMI) affects whether the transfer can be done as planned and if it leads to pregnancy. Researchers compared obese and non-obese women using different hormone preparation methods. Th…

This study looked at 30 women with advanced ovarian cancer to count and examine tumor cells found in their blood. The goal was to see if these cells could help predict how the disease might progress or respond to treatment. The results may lead to better ways to monitor the disea…

This study tested whether a peer ambassador program could help more gynecologic cancer patients learn about and join clinical trials. Twenty-three patients with advanced or recurrent gynecologic cancer were paired with a mentor who had personal experience with cancer and clinical…

This study reviewed 575 adults admitted to intensive care for a severe kidney infection called acute obstructive pyelonephritis. Researchers aimed to identify factors that lead to poor outcomes such as death or lasting kidney damage. The goal is to better understand which patient…

This study looked at how a genetic test that checks 25 genes linked to hereditary cancers is used in clinics. Over 1,500 people with a personal or family history of cancer took part. Researchers collected blood samples and had participants fill out questionnaires over five years …

This study tested a special stitch device (STRATAFIX Spiral PDS Plus) used in robot-assisted surgeries for weight loss (sleeve gastrectomy) and hysterectomy. 161 adults took part. The main goal was to see how well it controlled bleeding after stitching. Doctors also rated how eas…

This completed study followed 40 women who had standard surgery for gynecologic cancers (endometrial, cervical, ovarian, or fallopian tube). Researchers measured changes in quality of life and checked for lower limb lymphedema (leg swelling). The goal was to learn how surgery aff…

This study looked at 3000 cancer patients to see which treatments work best for preventing dangerously low white blood cell counts after chemotherapy. It compared different approaches to see how well they prevent infections and improve quality of life. The goal is to give doctors…

This study looked at how a single round of chemotherapy or immunotherapy changes the way the body uses energy and fats in women with gynecologic cancers. Researchers measured breathing and blood markers in 43 participants before and after treatment. The goal was to learn more abo…

This study looked at whether giving women a self-collection kit for HPV testing at their family doctor's office would encourage more women to get screened for cervical cancer. The study involved 308 women aged 30-65 who were overdue for screening. Some women were offered the usua…

This study involved 40 pregnant women whose babies were not growing well (fetal growth restriction). Researchers wanted to see if a single session of moderate exercise would change the baby's well-being. They measured the baby's health using ultrasound before and after the exerci…

This completed study surveyed 1,200 women aged 18-55 to explore how different generations manage menstrual symptoms like cramps, pain, and related discomfort. Participants completed questionnaires about their symptoms, attitudes toward menstruation, sleep quality, physical activi…

This study tested whether motivational interviews based on the Health Belief Model could increase HPV-DNA testing among women aged 30-45 who hadn't been tested in five years. Researchers gave 4 sessions of motivational interviewing and educational materials to one group, while a …

This study looked at how different doses and methods of giving progesterone (vaginal, under the skin, or muscle injection) affect the structure and function of the uterine lining in women preparing for embryo transfer. 109 healthy women with regular cycles took part, and research…

This study looked back at the medical records of 293 women who had surgery to remove uterine fibroids (myomectomy). The goal was to find out how often a hysterectomy (removal of the uterus) was needed during the procedure and what complications occurred within 30 days after surge…

This completed study looked at how often fallopian tubes are completely removed when women have surgery to remove an ovary and tube (adnexectomy). The goal was to improve the surgical technique to lower the risk of ovarian cancer. 115 women participated, and researchers checked f…

This completed study tested an artificial intelligence (AI) model to automatically detect endometriosis lesions in real time during laparoscopic surgery. Researchers used video recordings from 26 patients to train and validate the AI. The goal was to see if the AI could accuratel…

This study compared robot-assisted laparoscopy using the Senhance Surgical System to conventional laparoscopy for hysterectomy and other uterine surgeries. Researchers measured operating time, blood loss, and safety in 78 patients. The goal was to see if the robot offers advantag…

This study looked at tissue samples from 15 women with deep endometriosis who had laparoscopic surgery. Researchers measured nerve and blood vessel density in the peritoneum near endometriosis nodules and checked pain scores before and after surgery. The goal was to see if these …

This study looked at 255 women who chose to have permanent sterilization (tubal ligation) surgery. Researchers compared three different surgical approaches to see which one led to the best recovery and highest patient satisfaction. The goal was to help doctors and patients choose…

This completed observational study looked at 150 women to see how different types of fibroid removal surgery (hysteroscopic, laparoscopic, or laparotomic) affect pregnancy outcomes. It compared women who had surgery with those who did not, and also looked at whether surgery durin…

This study looked at 267 women with early-stage cervical cancer to compare two surgical approaches: removing all pelvic lymph nodes versus removing only the sentinel (first) lymph node. The goal was to see which method causes fewer complications within 6 months after surgery. Res…