Friendly bacteria vs. yeast: can a probiotic stop infections from coming back?

NCT ID NCT07727967

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether taking a specific probiotic supplement (Lactobacillus crispatus Lc-G22) alongside standard antifungal treatment can help prevent repeat vaginal yeast infections. One hundred women with a history of frequent yeast infections will receive either the probiotic or a placebo for two months. Researchers will track how many women remain infection-free over the following year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a probiotic supplement containing live Lactobacillus crispatus Lc-G22 bacteria
What this could lead to
If effective, this probiotic could offer a simple, non-drug way to reduce the frequency of recurrent yeast infections in women.
What could go wrong
This is a small, early-stage trial, and probiotics may not work for everyone. Some people may experience digestive discomfort or other mild side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Third Affiliated Hospital of Southern Medical University

    Guangzhou, Guangdong, China

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