Could a contraceptive gel ward off vaginal infections?
NCT ID NCT05753813
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tests whether a lactic acid gel (Phexxi) used twice weekly can change the vaginal microbiome to help prevent recurrent bacterial vaginosis and yeast infections. 22 premenopausal women with a history of these infections will use the gel for 4 weeks. Researchers will track changes in vaginal bacteria and symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lactic acid gel (Phexxi)
- What this could lead to
- If it works, this could point toward a non-antibiotic way to prevent recurrent vaginal infections by boosting healthy bacteria.
- What could go wrong
- This is a very early, small study with only 22 people. It may not show a clear benefit, and results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Queens Medical Center, 1004 Clinic POB1
RECRUITINGHonolulu, Hawaii, 96813, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Friendly bacteria vs. vaginal infections: a new trial puts probiotics to the test
- Can we finally outsmart recurrent yeast infections? a new study investigates
- Can a simple Self-Test cut preterm births in High-Risk pregnancies?
- Friendly bacteria vs. yeast: can a probiotic stop infections from coming back?
- Vaginal device aims to boost infection treatment
- Blue light could soothe vaginal disorders without hormones