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New drug combo shows promise in Hard-to-Treat cancers

NCT ID NCT06108479

Completed Disease control Sponsor: Dragonfly Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a new drug called DF6215, alone or with another drug (pembrolizumab), in 35 adults with advanced solid tumors that could not be removed by surgery or had spread. The main goals were to find the safest dose and check for side effects. The study is complete, but results are not yet available.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer Head and Neck Neoplasms melanoma neoplasm non-small cell lung carcinoma ovarian cancer renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMOR CANCER SOLID TUMOR, ADULT

Contacts and locations

Locations

  • CHU de Marseille - Hôpital de la Timone

    Marseille, 13005, France

  • Cancer Research SA (CRSA)

    Adelaide, South Australia, 5000, Australia

  • Centre Georges François Leclerc

    Dijon, 21000, France

  • Centre Hospitalier Universitaire de Bordeaux

    Bordeaux, 33075, France

  • Centre Hospitalier Universitaire de Poitiers

    Poitiers, 86000, France

  • Hôpital Lyon-Sud

    Pierre-Bénite, 69495, France

  • Institut Bergonié

    Bordeaux, 33000, France

  • Institut Curie

    Paris, 75005, France

  • Institut Paoli-Calmettes

    Marseille, 13009, France

  • Institut Universitaire du Cancer de Toulouse Oncopole

    Toulouse, 31100, France

  • Institut de Cancérologie de l'Ouest - Saint-Herblain - Site René Gauducheau

    Saint-Herblain, 44805, France

  • Lifespan - Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • Peninsula and South East Oncology Medical (PASO)

    Frankston, Victoria, 3199, Australia

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

  • Sarcoma Oncology Center

    Santa Monica, California, 90403, United States

  • Tampa General Hospital

    Tampa, Florida, 33606, United States

  • The Angeles Clinic and Research Institute - West Los Angeles Office

    Los Angeles, California, 90025, United States

  • University of California Irvine Medical Center

    Orange, California, 92868, United States

  • University of California San Diego Moores Cancer Center

    San Diego, California, 92093, United States

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