Can a genetic trait stop chemotherapy from working? a trial aims to fix that

This trial is testing whether a new dosing algorithm can help people with a genetic trait called Duffy-null get the full benefit of chemotherapy. Many people of African or Middle Eastern descent naturally have lower white blood cell counts (Duffy-null neutropenia), which can lead doctors to reduce or delay chemo doses. The study first develops an algorithm to guide dosing, then tests it in a larger group to see if it keeps treatment on track without increasing risks.