Could an arthritis drug boost IVF success in endometriosis patients?

NCT ID NCT07509411

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving an anti-inflammatory drug (anti-TNFα) a few days before a frozen embryo transfer can help women with endometriosis who have had a failed IVF cycle get pregnant. The trial involves 145 participants and compares the clinical pregnancy rate to standard care. The goal is to see if reducing inflammation improves the womb's ability to accept an embryo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TNF-α inhibitor (a drug that blocks inflammation)

What this could lead to

If it works, this could offer a new treatment option to improve pregnancy chances for women with endometriosis who have failed previous IVF attempts.

What could go wrong

This is a small, early-phase trial (145 participants) and results may not apply to all endometriosis patients. The drug may not improve pregnancy rates and could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ENDOMETRIOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Benha university

    Banhā, El Qalyoubia, 13511, Egypt