Letting patients decide when to stop antibiotics: a pilot study

NCT ID NCT06127160

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tested whether women with kidney infections could safely stop antibiotics once their symptoms resolved, instead of taking a full 10-day course. 35 women were randomly assigned to either standard treatment or a patient-directed approach. The main goal was to see if such a study is feasible and safe, not to prove effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cephalexin

What this could lead to

If successful, this could lead to shorter, more personalized antibiotic courses for kidney infections, reducing side effects and antibiotic resistance.

What could go wrong

This is a very small pilot study (35 participants) testing feasibility, not effectiveness. The approach may not work for everyone or could lead to higher relapse rates.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PYELONEPHRITIS ACUTE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute pyelonephritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Olive View - UCLA Medical Center

    Sylmar, California, 91342, United States

  • University of Iowa Hospitals and Clinics

    Iowa City, Iowa, 52242, United States