Which antibiotic works best to prevent early labor in High-Risk pregnancies?
NCT ID NCT01722708
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two common antibiotics, clindamycin and metronidazole, taken orally for a week to treat abnormal vaginal flora in pregnant women at high risk for preterm labor. The goal was to see which drug better clears the infection and reduces risks like early delivery. 166 women participated, and researchers tracked side effects and pregnancy outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Clindamycin and metronidazole (oral antibiotics)
- What this could lead to
- If one antibiotic works better, it could help prevent preterm labor in high-risk pregnancies by clearing abnormal vaginal flora.
- What could go wrong
- This is a small, completed trial with 166 participants, so results may not apply to all pregnant women. Both drugs can cause side effects like stomach upset or allergic reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Departement of obstetric and gynecology, HaEmek medical center
Afula, Israel
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Departement of obstetric and gynecology, Poriya Medical Center
Tiberias, Israel, Israel