Could a common painkiller combo ease cancer treatment pain?
NCT ID NCT02439034
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding ketoprofen to standard paracetamol (acetaminophen) can better control pain in patients receiving brachytherapy for cervical or upper airway/digestive tract cancers. Sixty-eight adults were randomly assigned to receive either paracetamol alone or paracetamol plus ketoprofen during and after the procedure. The goal was to see if the combination kept pain below a score of 4 out of 10, four hours after surgery, and to track pain levels throughout recovery at home.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Paracetamol and ketoprofen
What this could lead to
If successful, this could establish a standard pain management protocol for brachytherapy patients, reducing pain and improving quality of life during and after treatment.
What could go wrong
This is a small phase 2 trial with only 68 participants, so results may not apply to all patients. Adding ketoprofen may increase side effects like stomach or kidney issues.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centre Oscar Lambret
Lille, 59020, France