Centre Oscar Lambret

This study tests a special low-dose chemotherapy schedule (metronomic chemo) in children aged 1.5 to 17 years whose Wilms tumor has come back or not responded to standard treatments. The goal is to see if this approach can control the disease after two treatment cycles. About 28 …

This study looks at whether giving the HPV vaccine to women over 45 who still have HPV after treatment for high-grade cervical lesions can help clear the virus. About 85 women will either get the vaccine or be observed without it. The main goal is to see how many become HPV-free …

This study tests whether a gentle radiofrequency treatment inside the vagina can reduce dryness and pain in breast cancer patients taking hormone therapy. About 75 women will either receive standard moisturizers alone or moisturizers plus three radiofrequency sessions. The goal i…

This study tests three treatments—nerve block, Botox, and capsaicin—to relieve chronic nerve pain after mastectomy that standard painkillers can't control. 123 women will be randomly assigned to one of the three groups and followed for 24 weeks. The main goal is to see which trea…

This study looks at whether a Snoezelen multisensory relaxation room can reduce anxiety in children and teens (ages 8-17) who are hospitalized for chemotherapy. Twenty participants will compare their feelings during a chemo cycle without Snoezelen to a later cycle where they have…

This study is creating a detailed database of 651 adults with solid tumors who are starting immunotherapy. Researchers will track their health over 5 years to see how well these treatments work in everyday medical practice. The goal is to learn more about outcomes like survival a…

This study is collecting information from 371 people with advanced ovarian, peritoneal, or fallopian tube cancer to find out which factors affect how long they live. Researchers will look at patient details like age and health, as well as tumor features like genetics and cell typ…

This study collects tumor and blood samples from 100 breast cancer patients to grow mini-tumors (organoids) in the lab. Researchers will then test whether specially engineered immune cells called CAR-macrophages can kill these organoids. The goal is to learn which types of breast…

This study looks at whether a digital, personalized care plan can help people with advanced sarcoma who are on chemotherapy. About 377 participants will either get the digital plan plus standard care, or standard care alone. The main goal is to see if the digital plan reduces sev…

This study looks at whether follow-up care for people with rare tumors can be done just as well by a nurse remotely as by a doctor in person. About 88 adults recently diagnosed with a rare tumor will be randomly assigned to either in-person doctor visits or remote nurse check-ins…