Centre Oscar Lambret

This large, late-stage trial is testing whether adding a special heated chemotherapy wash to standard surgery helps people with advanced ovarian cancer stay cancer-free for longer. The study compares two groups: one receives the heated chemo during their tumor-removal surgery, an…

This study explores whether freezing eggs or embryos before chemotherapy is safe and feasible for young women with early breast cancer. It aims to preserve their future fertility options while managing cancer treatment. Researchers will track egg quality, pregnancy rates, and can…

This study aims to track side effects and quality of life in breast cancer patients receiving standard radiotherapy after surgery. It will follow 500 patients for two years after treatment to record their experiences. The goal is to better understand how this common treatment aff…

This trial is testing whether adding an immunotherapy drug called nivolumab to a specific low-dose chemotherapy regimen can help control cancer in children and teenagers whose solid tumors have come back or didn't respond to standard treatments. The study first checked if the com…

This study aimed to see if analyzing tiny particles in spinal fluid could help doctors better detect when breast cancer spreads to the lining of the brain and spinal cord. It planned to enroll patients already suspected of having this serious complication. The goal was to compare…

This study compares two surgical approaches for checking if early-stage uterine cancer has spread to nearby lymph nodes. One method removes many lymph nodes, while the other uses a 'sentinel node' technique to find and test just the first few nodes where cancer would likely sprea…

This study is testing a specific, less invasive surgery for women with BRCA gene mutations who are at high risk for ovarian cancer. The surgery removes the ends of the fallopian tubes, where this cancer often starts, while leaving the ovaries intact to preserve natural hormone pr…

This study follows young breast cancer survivors for 10 years to understand how chemotherapy affects their long-term fertility and ability to have children. Researchers are comparing outcomes between patients who underwent fertility preservation procedures and those who did not. …

This study aims to build the largest French database of patients with aggressive fibromatosis, a rare and unpredictable non-cancerous tumor. By tracking over 600 patients, researchers hope to understand how the disease behaves, what factors influence its progression, and how diff…

This study aims to understand why some advanced breast cancers become resistant to the drug palbociclib. Researchers will follow 25 women with hormone-positive breast cancer, collecting tumor samples and breath/body fluid samples before treatment and when the cancer progresses. B…

This study aims to understand what helps head and neck or lung cancer patients stay smoke-free after completing radiation or chemo-radiation treatment. Researchers will follow 100 patients for one year after treatment, checking in at 1, 6, and 12 months to track their smoking sta…