Centre Oscar Lambret

This study tested whether adding weekly chemotherapy with carboplatin and paclitaxel after standard chemoradiation could help people with advanced cervical cancer that has spread to lymph nodes near the aorta. The trial enrolled 21 adults and aimed to see if this extra treatment …

This study tested the drug imatinib in 13 adults with ocular melanoma that had spread to other parts of the body. The goal was to see if the drug could stop or slow tumor growth. The trial was stopped early, and results were limited.

This study tested a temporary, biodegradable balloon placed between the prostate and rectum during radiation therapy for intermediate-risk prostate cancer. The goal was to see if the balloon could reduce radiation damage to the rectum by creating more space. The study enrolled 24…

This study tested a new treatment plan for people with advanced cervical cancer (stages IB2 to IVA). The plan combined radiation and chemotherapy (cisplatin and gemcitabine) followed by more chemotherapy with gemcitabine. The goal was to see if this sequence could improve how lon…

This study tested a technique called Narrow Band Imaging (NBI) that uses special light to help surgeons see early cancer spots in the mouth that are hard to detect with the naked eye. The goal was to see if NBI could help remove all cancer tissue during surgery. The trial include…

This study looked at whether giving radiation to the brain early could prevent cancer from spreading there in people with HER2-positive breast cancer that had already spread to other organs. All participants were receiving trastuzumab (Herceptin) plus chemotherapy. The study was …

This study looked at whether a mechanical stimulation technique could reduce pain and improve shoulder function better than standard massages in women who had a total mastectomy and lymph node removal for breast cancer. About 80 participants were planned, but the study was stoppe…

This study tested a special technique that combines organizing traumatic memories with slow, deep breathing to reduce PTSD symptoms in people with advanced cancer and their partners. The goal was to see if this approach could lower stress, inflammation, and possibly improve survi…

This study looked at how radiosurgery (a precise type of radiation) impacts the quality of life of people with brain metastases that have spread from other cancers. Researchers tracked 52 patients over 12 months using questionnaires about physical function, thinking, mood, and da…

This study looked at how the immune system responds during high-dose radiation therapy in people with liver, colorectal, melanoma, or kidney cancers. Researchers collected blood samples before, during, and after treatment to track immune cells and other markers. The goal was to l…

This study aimed to see if MRI and PET scans could predict whether radiotherapy is controlling cervical cancer. It included 9 patients with stage I to IIIB cervical cancer who were receiving chemoradiotherapy. The study was terminated early, so results are limited.

This study looked at why people with mouth or throat cancer delay their first doctor visit. Researchers examined emotional, social, and medical factors in 90 adults with untreated cancer. The goal was to understand what influences how quickly someone seeks help after noticing sym…

This study aimed to understand how chemotherapy affects the ability to have children in young women (ages 18-37) with breast cancer. Researchers measured changes in ovarian reserve (egg supply) over two years. The goal was to provide better fertility information and help personal…

This study looked at 21 adults with advanced lung cancer to see if a blood test (liquid biopsy) could detect EGFR gene mutations as accurately as a standard tumor tissue biopsy. The goal was to find a less invasive way to guide treatment decisions. The study was terminated early,…

This study collected blood, fluid, and tissue samples from 36 women with advanced ovarian or fallopian tube cancer to analyze immune cells before and after chemotherapy. The goal was to understand how the immune system responds to the cancer and treatment. The study was terminate…

This study looked at whether the types of bacteria in a person's gut before treatment could predict how well their rectal cancer responds to chemotherapy and radiation. Researchers planned to collect stool samples from patients with stage II or III rectal cancer and compare their…

This study aimed to find out if patients with metastatic esophageal cancer who were not getting worse after 6 weeks of chemotherapy should continue treatment or stop. Only 15 people took part before the study was ended early. The goal was to see if continuing chemo helped patient…

This study aimed to find the best cell source for creating a non-stick patch to prevent adhesions in cancer patients. Researchers compared cells from the peritoneum and from fat tissue, growing them in a lab to see which formed the right type of cells. The study was terminated ea…

This study looked at whether chest X-rays or CT scans are better for finding lung cancer spread in people who had surgery for high-grade soft tissue sarcoma. The goal was to see which test helps catch lung tumors early enough for surgery. Only 11 people joined before the study wa…

This study looked at why some breast cancer cells, called cancer stem cells, survive chemotherapy and cause the cancer to come back. Researchers collected tumor and blood samples from 56 women before, during, and after chemotherapy to find the genes and processes that help these …

This study looked at whether early, personalized support could help women with breast cancer return to work better than standard care. It involved 128 women who had surgery and chemotherapy. The study was terminated early, so results are limited.