Centre Oscar Lambret

This study tested whether adding extra chemotherapy after standard radiation treatment could help control advanced cervical cancer that had spread to nearby lymph nodes. It involved patients who first completed standard radiation and chemotherapy, then received additional weekly …

This study tested whether the drug imatinib could help control metastatic ocular melanoma, a serious cancer that starts in the eye and spreads. It involved 13 adult patients whose cancer had spread to other parts of their body. The main goal was to see if the treatment could stop…

This study tested a new approach to reduce side effects from radiation treatment for intermediate-risk prostate cancer. Researchers implanted a small, biodegradable balloon between the prostate and rectum to create space and protect healthy tissue. They measured if this allowed f…

This study aimed to find out if continuing chemotherapy helps people with advanced esophageal cancer that hasn't gotten worse after initial treatment. All participants received 6 weeks of chemotherapy first. Those whose cancer hadn't progressed were then randomly assigned to eith…

This study tested whether a special imaging technique called Narrow Band Imaging (NBI) could help surgeons see the edges of oral cancer tumors more clearly during surgery. It involved 23 adults with newly diagnosed, untreated oral cavity cancer who were scheduled for surgery. The…

This study tested whether giving preventive radiation to the brain could stop cancer from spreading there in people with advanced HER2-positive breast cancer already receiving targeted drug therapy (trastuzumab). It aimed to see if this approach helped patients live longer withou…

This study tested whether early, personalized psychological support helps women with breast cancer return to work after treatment. Researchers compared women who received four counseling sessions with a psychologist during and after treatment to those who received standard suppor…

This study aimed to understand how radiosurgery treatment affects the quality of life of patients with brain metastases. Fifty-two patients with up to five brain tumors answered detailed questionnaires about their physical, mental, and cognitive well-being before treatment and fo…

This study tested a brief phone-based therapy to help patients and their partners cope with the emotional trauma of receiving news that their cancer is advanced and incurable. The therapy combined deep breathing exercises with a technique to help people structure their traumatic …

This study aimed to see if a mechanical stimulation device works better than standard massage to reduce pain and improve shoulder movement for breast cancer patients after mastectomy surgery. It planned to enroll 80 patients needing physical therapy and compare their pain levels,…

This study aimed to understand why some breast cancer cells become resistant to chemotherapy. Researchers analyzed tumor and blood samples from 56 women before, during, and after standard chemotherapy treatment. The goal was to learn how certain aggressive 'cancer stem cells' eme…

This study aimed to see if a simple blood test (liquid biopsy) could be as accurate as a traditional tissue biopsy for finding specific genetic changes in lung cancer. Researchers compared results from both methods in 21 patients with advanced lung cancer who had not yet started …

This study aimed to learn how the body's immune cells behave in women with advanced ovarian or fallopian tube cancer. Researchers collected blood and tissue samples from 36 participants before and after their standard chemotherapy treatment. The goal was to describe the immune sy…

This study aimed to understand how standard chemotherapy treatments for breast cancer affect the future fertility of young women. Researchers followed 135 women under age 38, measuring key hormones and ovarian markers before, during, and for two years after chemotherapy. The goal…

This study aimed to understand why people with head and neck cancers delay seeing a doctor after first noticing symptoms. Researchers interviewed 90 patients to learn how emotional, social, and personal factors affect when people seek medical help. The goal was to identify barrie…

This was a laboratory study that tested two different sources of human cells to see which one could be better for making a non-stick medical patch. Researchers collected small tissue samples from six patients during surgery and grew the cells in a lab. The goal was to compare the…

This study aimed to see if the types of bacteria in a person's gut before starting cancer treatment could predict how well their rectal tumor would respond to chemotherapy and radiation. It was a small, observational study that only enrolled two patients before it was stopped. Re…

This study aimed to understand how high-dose radiation therapy affects the body's immune system in patients with liver, colorectal, skin, or kidney cancers. Researchers collected blood samples from 28 patients before, during, and after radiation treatment to measure immune cell c…

This study aimed to understand why some cervix cancers return after standard radiation and chemotherapy treatment. Researchers tested whether persistent tumor hypoxia (low oxygen levels) during early treatment could predict whether the cancer would be controlled locally. The stud…