Can retelling and deep breathing ease trauma in terminal cancer?

NCT ID NCT03652298

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This Phase 2 trial tested a neuroscience-based technique combining memory structuring and deep vagal breathing to reduce PTSD symptoms in people with advanced, incurable cancer and their partners. The study enrolled 19 patients who had just received a terminal diagnosis. The approach aimed to help them process the traumatic news by organizing memories and using paced breathing to calm the nervous system. The trial was terminated early, so firm conclusions cannot be drawn.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Memory structuring intervention plus vagal breathing
What this could lead to
If it works, this could point toward a non-drug technique to reduce PTSD symptoms in people with advanced cancer.
What could go wrong
The trial was terminated early with only 19 participants, so results are very limited. It is unclear if the approach is effective or safe in this setting.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Oscar Lambret

    Lille, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.