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Brain radiation for breast cancer: prevention study halted early

NCT ID NCT01613482

Terminated Prevention Sponsor: Centre Oscar Lambret Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving radiation to the brain could prevent cancer from spreading there in people with HER2-positive breast cancer that had already spread to other organs. Participants were receiving trastuzumab (Herceptin) plus chemotherapy. The study was stopped early because not enough people enrolled, so we don't have clear answers.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm HER2 positive breast carcinoma metastatic neoplasm Neoplasm Metastasis metastatic malignant neoplasm in the brain prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER METASTASIS SUR-EXPRESSING HER2-NEU

Contacts and locations

Locations

  • CHU Dupuytren

    Limoges, 87042, France

  • Centre Alexis Vautrin

    Vandœuvre-lès-Nancy, 54511, France

  • Centre Antoine Lacassagne

    Nice, 06189, France

  • Centre Azuréen de Cancérologie

    Mougins, 06250, France

  • Centre Bourgogne

    Lille, 59000, France

  • Centre Catalan d'Oncologie

    Perpignan, 66000, France

  • Centre Catherine de Sienne

    Nantes, 44202, France

  • Centre Etienne DOLET

    Saint-Nazaire, 44600, France

  • Centre G-François Baclesse

    Caen, 14076, France

  • Centre Hospitalier

    Boulogne-sur-Mer, 62200, France

  • Centre Hospitalier LYON SUD

    Pierre-Bénite, 69495, France

  • Centre Hospitalier de Mulhouse

    Mulhouse, 68100, France

  • Centre Léonard de Vinci

    Dechy, 59187, France

  • Centre Maurice Tubiana

    Caen, 14052, France

  • Centre Médical de Forcilles

    Forcilles-attilly, 77150, France

  • Centre Oscar LAMBRET

    Lille, 59020, France

  • Centre Paul Papin

    Angers, 49933, France

  • Centre René Huguenin

    Saint-Cloud, 92210, France

  • Centre de Cancérologie Paris Nord

    Sarcelles, 95200, France

  • Centre médical Oncogard

    Nîmes, 30907, France

  • Clinique Clinique Clementville

    Montpellier, 34000, France

  • Clinique Hartmann

    Neuilly-sur-Seine, 92200, France

  • Clinique des Ormeaux- Vauban

    Le Havre, 76600, France

  • Hôpital Tenon

    Paris, 75020, France

  • Institut Gustave Roussy

    Villejuif, 94805, France

  • Oncorad Garonne

    Toulouse, 31400, France

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