Heated chemotherapy during surgery may delay ovarian cancer return
NCT ID NCT03842982
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial tests whether giving heated chemotherapy directly into the abdomen during surgery can help people with advanced ovarian cancer live longer without the disease coming back. About 362 participants will either receive standard surgery alone or surgery plus the heated chemotherapy. The study is active but no longer recruiting, and results are awaited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cisplatin (heated chemotherapy given directly into the abdomen during surgery)
What this could lead to
If successful, this could offer a way to delay ovarian cancer recurrence after surgery, giving patients more time without the disease progressing.
What could go wrong
This is a phase 3 trial, but results are not yet final. The heated chemotherapy adds complexity and risk of side effects, and it may not improve survival for all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centre François Baclesse
Caen, 14076, France
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Centre Henri Becquerel
Rouen, France
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Centre Hospitalier Lyon Sud
Pierre-Bénite, 69495, France
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Centre Jean Perrin
Clermont-Ferrand, 63011, France
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Centre Oscar Lambret
Lille, 59020, France
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Clinique Mathilde
Rouen, 76100, France
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Cliniques universitaires St-Luc, Institut Roi Albert II
Brussels, 1200, Belgium
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Hôpital Européen Georges Pompidou
Paris, 75008, France
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Hôpital Jeanne de Flandre
Lille, 59037, France
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Hôpital de Hautepierre
Strasbourg, France
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ICM-Val d'Aurelle
Montpellier, 34298, France
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Institut Bergonié
Bordeaux, 33076, France
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Institut Gustave Roussy
Villejuif, 94805, France
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Institut Jules Bordet
Brussels, 1070, Belgium
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Institut Paoli Calmettes
Marseille, 13273, France
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Institut de Cancérologie de Lorraine
Vandœuvre-lès-Nancy, 54519, France
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Institut de Cancérologie de l'Ouest
Angers, 49055, France
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Institut de Cancérologie de l'Ouest
Saint-Herblain, 44800, France