Lab-Grown tumors used to test supercharged immune cells against breast cancer
NCT ID NCT05007379
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study collects tumor and blood samples from 100 breast cancer patients to grow mini-tumors (organoids) in the lab. Researchers will then test whether specially engineered immune cells called CAR-macrophages can destroy these mini-tumors. The goal is to see if this new cell therapy could be a future treatment for different types of breast cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CAR-macrophages
- What this could lead to
- If the CAR-macrophages show strong activity against the organoids, this could point toward a new cell-based treatment for breast cancer.
- What could go wrong
- This is a very early lab study using tumor samples, not a treatment trial in patients. The approach may not work in real bodies or may have unexpected side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Oscar Lambret Center
RECRUITINGLille, 59000, France
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