New shorter radiation regimen aims to improve sarcoma treatment
NCT ID NCT07507773
First seen Jun 25, 2026 · Last updated Jul 24, 2026 · Updated 3 times
Summary
This phase 2 trial is testing a shorter, more intense radiation schedule given before surgery for soft tissue sarcoma in the arms, legs, or trunk. The goal is to see if this approach can keep the cancer from coming back in the same spot. About 135 adults will receive 15 radiation sessions over 3 weeks, followed by surgery, and then be monitored for up to 5 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- moderately hypofractionated radiotherapy (15 sessions over 3 weeks)
- What this could lead to
- If successful, this shorter radiation schedule could become a standard option before surgery for soft tissue sarcoma, reducing treatment time while maintaining tumor control.
- What could go wrong
- This is a phase 2 trial with only 135 participants, so results are preliminary. The shorter radiation course may not control the tumor as well as standard longer regimens, and side effects could differ.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SOFT TISSUE SARCOMA (EXCLUDING GIST) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre Oscar Lambret
RECRUITINGLille, 59000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could 5 days of radiation replace 25 for sarcoma patients?
- New drug cocktail aims to halt sarcoma progression
- 800-Patient study aims to tailor sarcoma treatment
- Hitchhiking drug targets Hard-to-Treat cancers in early trial
- Virus plus radiation may shrink sarcomas before surgery
- Experimental drug combo targets sarcoma before surgery