New shorter radiation regimen aims to improve sarcoma treatment

NCT ID NCT07507773

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing a shorter, more intense radiation schedule given before surgery for soft tissue sarcoma in the arms, legs, or trunk. The goal is to see if this approach can keep the cancer from coming back in the same spot. About 135 adults will receive 15 radiation sessions over 3 weeks, followed by surgery, and then be monitored for up to 5 years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

moderately hypofractionated radiotherapy (15 sessions over 3 weeks)

What this could lead to

If successful, this shorter radiation schedule could become a standard option before surgery for soft tissue sarcoma, reducing treatment time while maintaining tumor control.

What could go wrong

This is a phase 2 trial with only 135 participants, so results are preliminary. The shorter radiation course may not control the tumor as well as standard longer regimens, and side effects could differ.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Oscar Lambret

    RECRUITING

    Lille, 59000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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