Could 5 days of radiation replace 25 for sarcoma patients?
NCT ID NCT07615049
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a short course of radiation therapy (5 days) to the standard longer course (25 days) for people with soft tissue sarcoma in the arms or legs that can be removed with surgery. The goal is to see if the shorter treatment is just as effective at preventing the cancer from coming back, while being more convenient. About 296 participants will be randomly assigned to one of the two radiation schedules before their surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiation therapy
- What this could lead to
- If this shorter radiation course works, it could become a new standard that saves patients weeks of daily hospital visits without increasing the risk of the cancer coming back.
- What could go wrong
- This is an early-stage comparison, and the shorter course might not control the tumor as well as the longer one. There is also a risk of more severe side effects from the higher daily radiation doses.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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