Blood test may replace surgery for endometriosis diagnosis

NCT ID NCT07586488

Completed Diagnosis Sponsor: Zagazig University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether measuring certain molecules in the blood (microRNAs) can accurately detect early-stage endometriosis. Researchers compared the blood test results to the standard surgical diagnosis in 60 women. The goal is to find a non-invasive way to diagnose endometriosis earlier, avoiding the risks and costs of surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: blood test for microRNA 125b-5p and 141-3p
What this could lead to: If successful, this blood test could allow earlier, non-invasive diagnosis of endometriosis, reducing the need for exploratory surgery.
What could go wrong: This is a small, completed study with only 60 participants. The test's accuracy may not hold up in larger, more diverse groups, and it is not yet ready for clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIOSIS

Contacts and locations

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Locations

Benha University

Banhā, Al Qalyoubia, 13511, Egypt

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