Can Pre-Surgery pelvic floor therapy stop endometriosis pain after the operation?
NCT ID NCT07827794
First seen Sep 18, 2026 · Last updated Sep 18, 2026
Summary
Endometriosis is a long-term condition where tissue like the uterine lining grows outside the uterus, often causing lasting pelvic pain. Surgery can help, but pain sometimes remains afterward. Researchers are testing whether a structured pelvic floor physiotherapy program done before surgery, called prehabilitation, reduces pain and improves quality of life. Participants are randomly assigned to receive the pre-surgery physiotherapy plus usual care, or usual care alone, and they answer questionnaires about pain, bladder and bowel symptoms, and mental well-being for up to a year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A structured pelvic floor physiotherapy program done before surgery
- What this could lead to
- If it works, pelvic floor therapy before surgery could become a standard step to help people with endometriosis avoid long-lasting pain after their operation.
- What could go wrong
- This is a single trial in one health system, and physiotherapy may not help everyone. Surgery and recovery vary, so results might not apply broadly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2027
An estimate. Start dates often move.
- Expected to finish
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Sep 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Presence of chronic pelvic pain (\>6 months) * Diagnosis of endometriosis (clinical, laparoscopic, or imaging-based diagnosis) * Scheduled for fertility-sparing endometriosis surgery or hysterectomy with excision of endometriosis Exclusion Criteria: * Undergoing gynecologic surgery in the absence of pelvic pain * Patients undergoing laparotomy or conversion to laparotomy * Have undergone endometriosis related surgery in the past 12 months * Have engaged in pelvic physiotherapy in the past 12 months * Non-English speakers (if validated tools unavailable) * Active malignancy * Post-menopausal * Prior oophorectomy * Prior hysterectomy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alberta
Edmonton, Alberta, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Two-Hour class rewire how women feel chronic pelvic pain?