Old drug, new hope: cabergoline trial targets endometriosis pain
NCT ID NCT03928288
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether cabergoline, a drug already used for other conditions, can reduce chronic pain in women and teens with endometriosis. 129 participants took either cabergoline or a placebo for 6 months. The goal was to see if this non-hormonal approach could safely ease pain without the side effects of standard hormone therapies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cabergoline (Dostinex)
What this could lead to
If it works, this could offer a new, non-hormonal option to ease chronic pain from endometriosis, avoiding side effects of current treatments.
What could go wrong
This is a phase 2 trial with 129 participants, so results are preliminary. The drug may not prove effective or could have side effects not yet seen.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02115, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Children's Hospital Boston
Boston, Massachusetts, 02115, United States
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Childrens Hospital Colorado
Aurora, Colorado, 80045, United States
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Standford University
Palo Alto, California, 94305, United States
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Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States