Heated chemo wash may stop colorectal cancer spreading in abdomen
NCT ID NCT01226394
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tested whether a surgical procedure called laparotomy plus heated chemotherapy (HIPEC) could improve outcomes for colorectal cancer patients at high risk of cancer spreading in the abdomen. 150 patients who had already undergone surgery and chemotherapy were randomly assigned to either standard follow-up or the additional surgery with HIPEC. The goal was to see if the extra treatment could increase the time patients lived without the cancer returning.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hyperthermic intraperitoneal chemotherapy (HIPEC)
What this could lead to
If successful, this could provide a way to prevent or delay the return of cancer in the abdomen for high-risk colorectal patients.
What could go wrong
This is a completed phase 3 trial, but results are not yet widely confirmed. The procedure is invasive and carries risks like infection or organ damage.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Institut Gustave Roussy
Villejuif, 94800, France