DNA 'Crystal Ball' may spot return of colorectal cancer

NCT ID NCT06314958

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study aims to develop a test that uses DNA methylation patterns from tumor samples to predict whether stage II or III colorectal cancer will return after surgery and chemotherapy. Researchers will analyze tissue from 400 patients who are currently cancer-free after treatment. The goal is to create a tool that identifies patients at higher risk of recurrence, potentially guiding more personalized follow-up care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a blood or tissue test that helps doctors know which patients need closer monitoring after colorectal cancer treatment.
What could go wrong
This is an early-stage study focused on developing and validating a test, not a treatment. The test may not prove accurate enough for routine use.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Barcelona University

    RECRUITING

    Barcelona, Spain

    Contact Email: •••••@•••••

    Contact

  • City of Hope Medical Center

    RECRUITING

    Monrovia, California, 91016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • La Paz University Hospital

    RECRUITING

    Madrid, Spain

    Contact Email: •••••@•••••

    Contact

  • Second Affiliated Hospital of Dalian Medical University

    RECRUITING

    Dalian, China

    Contact Email: •••••@•••••

    Contact

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