Cancer Survivors' sex drive gets a boost: bupropion shows promise

NCT ID NCT03180294

Completed Symptom relief Sponsor: NRG Oncology Source: ClinicalTrials.gov ↗

First seen Apr 28, 2026 · Last updated Apr 28, 2026

Summary

This study tested whether bupropion, a medication that affects brain chemicals, can improve low sexual desire in women who have had breast or gynecologic cancer. About 230 women took either bupropion or a placebo pill for 9 weeks. The main goal was to see if bupropion increased self-reported sexual desire more than the placebo, while also checking for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States
American Fork Hospital / Huntsman Intermountain Cancer Center

American Fork, Utah, 84003, United States
Annie Penn Memorial Hospital

Reidsville, North Carolina, 27320, United States
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Associates In Womens Health

Wichita, Kansas, 67208, United States
AtlantiCare Health Park-Cape May Court House

Cape May Court House, New Jersey, 08210, United States
AtlantiCare Surgery Center

Egg Harbor, New Jersey, 08234, United States
Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066, United States
Augusta University Medical Center

Augusta, Georgia, 30912, United States
Aurora Bay Area Medical Group-Marinette

Marinette, Wisconsin, 54143, United States
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Green Bay, Wisconsin, 54311, United States
Aurora Cancer Care-Grafton

Grafton, Wisconsin, 53024, United States
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Kenosha, Wisconsin, 53142, United States
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Milwaukee, Wisconsin, 53209, United States
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Wauwatosa, Wisconsin, 53226, United States
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Racine, Wisconsin, 53406, United States
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Burlington, Wisconsin, 53105, United States
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Germantown, Wisconsin, 53022, United States
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Fond du Lac, Wisconsin, 54937, United States
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Summit, Wisconsin, 53066, United States
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Cincinnati, Ohio, 45242, United States
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Billings, Montana, 59101, United States
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Bozeman, Montana, 59715, United States
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Des Moines, Iowa, 50314, United States
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New Richmond, Wisconsin, 54017, United States
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Flint, Michigan, 48503, United States
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Urbana, Illinois, 61801, United States
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Danville, Illinois, 61832, United States
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Centralia, Illinois, 62801, United States
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Cheyenne, Wyoming, 82001, United States
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Columbus Oncology and Hematology Associates Inc

Columbus, Ohio, 43214, United States
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Missoula, Montana, 59804, United States
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Scranton, Pennsylvania, 18510, United States
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Greensboro, North Carolina, 27403, United States
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Burlington, North Carolina, 27215, United States
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Mebane, North Carolina, 27302, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

Saint Joseph, Michigan, 49085, United States
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Niles, Michigan, 49120, United States
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Saint Joseph, Michigan, 49085, United States
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Reed City, Michigan, 49677, United States
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Springfield, Missouri, 65807, United States
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Effingham, Illinois, 62401, United States
Dayton Physician LLC - Englewood

Dayton, Ohio, 45415, United States
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Troy, Ohio, 45373, United States
Dayton Physicians LLC-Atrium

Franklin, Ohio, 45005, United States
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Centerville, Ohio, 45459, United States
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Greenville, Ohio, 45331, United States
Dayton Veterans Affairs Medical Center

Dayton, Ohio, 45428, United States
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Decatur, Illinois, 62526, United States
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Park Rapids, Minnesota, 56470, United States
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Duluth, Minnesota, 55805, United States
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Fargo, North Dakota, 58103, United States
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Hibbing, Minnesota, 55746, United States
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Brainerd, Minnesota, 56401, United States
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Detroit Lakes, Minnesota, 56501, United States
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Duluth, Minnesota, 55805, United States
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Virginia, Minnesota, 55792, United States
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Bardstown, Kentucky, 40004, United States
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Pottsville, Pennsylvania, 17901, United States
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Danville, Pennsylvania, 17822, United States
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Hazleton, Pennsylvania, 18201, United States
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State College, Pennsylvania, 16801, United States
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Selinsgrove, Pennsylvania, 17870, United States
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Wilkes-Barre, Pennsylvania, 18711, United States
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Flint, Michigan, 48503, United States
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Zanesville, Ohio, 43701, United States
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Fort Myers, Florida, 33905, United States
Genesys Hurley Cancer Institute

Flint, Michigan, 48503, United States
Gibbs Cancer Center-Gaffney

Gaffney, South Carolina, 29341, United States
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Greer, South Carolina, 29651, United States
Good Samaritan Hospital - Cincinnati

Cincinnati, Ohio, 45220, United States
Good Samaritan Hospital - Dayton

Dayton, Ohio, 45406, United States
Grant Medical Center

Columbus, Ohio, 43215, United States
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Kettering, Ohio, 45409, United States
Gulfport Memorial Hospital

Gulfport, Mississippi, 39502, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
HSHS Saint Nicholas Hospital

Sheboygan, Wisconsin, 53081, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo

Poulsbo, Washington, 98370, United States
Hawaii Cancer Care Inc - Waterfront Plaza

Honolulu, Hawaii, 96813, United States
Hawaii Cancer Care Inc-Liliha

Honolulu, Hawaii, 96817, United States
Health Partners Inc

Minneapolis, Minnesota, 55454, United States
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Hematology Oncology Consultants-Clarkston

Clarkston, Michigan, 48346, United States
Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States
Henry Ford Health Saint John Hospital

Detroit, Michigan, 48236, United States
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Warren, Michigan, 48093, United States
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East China Township, Michigan, 48054, United States
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Rochester Hills, Michigan, 48309, United States
Henry Ford Saint John Hospital - Academic

Grosse Pointe Woods, Michigan, 48236, United States
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Grosse Pointe Woods, Michigan, 48236, United States
Henry Ford Saint John Hospital - Macomb Medical

Macomb, Michigan, 48044, United States
Henry Ford Saint John Hospital - Van Elslander

Grosse Pointe Woods, Michigan, 48236, United States
Henry Ford Warren Hospital - Breast Macomb

Macomb, Michigan, 48044, United States
Henry Ford Warren Hospital - GLCMS

Warren, Michigan, 48093, United States
Holy Family Memorial Hospital

Manitowoc, Wisconsin, 54221, United States
Hope Cancer Clinic

Livonia, Michigan, 48154, United States
Hurley Medical Center

Flint, Michigan, 48503, United States
Indu and Raj Soin Medical Center

Beavercreek, Ohio, 45431, United States
Intermountain Health Lutheran Hospital

Wheat Ridge, Colorado, 80401, United States
Intermountain Medical Center

Murray, Utah, 84107, United States
Iowa Lutheran Hospital

Des Moines, Iowa, 50316, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
John H Stroger Jr Hospital of Cook County

Chicago, Illinois, 60612, United States
Kaiser Permanente - Panorama City

Panorama City, California, 91402, United States
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Sacramento, California, 95814, United States
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Dublin, California, 94568, United States
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Santa Clara, California, 95051, United States
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Modesto, California, 95356, United States
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San Rafael, California, 94903, United States
Kansas Institute of Medicine Cancer and Blood Center

Lenexa, Kansas, 66219, United States
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Honolulu, Hawaii, 96826, United States
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Kettering, Ohio, 45429, United States
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Mount Vernon, Ohio, 43050, United States
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Stillwater, Minnesota, 55082, United States
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Wynnewood, Pennsylvania, 19096, United States
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Lawrence, Kansas, 66044, United States
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New York, New York, 10075, United States
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Savannah, Georgia, 31405, United States
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Lewistown, Pennsylvania, 17044, United States
Licking Memorial Hospital

Newark, Ohio, 43055, United States
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Logan, Utah, 84321, United States
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New Orleans, Louisiana, 70112, United States
Macomb Hematology Oncology PC

Warren, Michigan, 48093, United States
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Hendersonville, North Carolina, 28791, United States
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Marietta, Ohio, 45750, United States
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Wisconsin Rapids, Wisconsin, 54494, United States
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Chippewa Falls, Wisconsin, 54729, United States
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Wausau, Wisconsin, 54401, United States
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Minocqua, Wisconsin, 54548, United States
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Weston, Wisconsin, 54476, United States
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Eau Claire, Wisconsin, 54701, United States
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Marshfield, Wisconsin, 54449, United States
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Rice Lake, Wisconsin, 54868, United States
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Stevens Point, Wisconsin, 54482, United States
McKay-Dee Hospital Center

Ogden, Utah, 84403, United States
Medical Oncology Hematology Consultants PA

Newark, Delaware, 19713, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Mercy Hospital Oklahoma City

Oklahoma City, Oklahoma, 73120, United States
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St Louis, Missouri, 63141, United States
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Springfield, Missouri, 65804, United States
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St Louis, Missouri, 63109, United States
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Des Moines, Iowa, 50314, United States
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Ballwin, Missouri, 63011, United States
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West Des Moines, Iowa, 50266-7700, United States
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Dayton, Ohio, 45409, United States
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Dayton, Ohio, 45415, United States
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Centerville, Ohio, 45459, United States
Michigan Healthcare Professionals Pontiac

Pontiac, Michigan, 48341, United States
Miller-Dwan Hospital

Duluth, Minnesota, 55805, United States
Minimally Invasive Surgery Hospital

Lenexa, Kansas, 66219, United States
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Maplewood, Minnesota, 55109, United States
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Woodbury, Minnesota, 55125, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
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Monticello, Minnesota, 55362, United States
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Englewood, Colorado, 80113, United States
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Auburn, Washington, 98001, United States
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Gig Harbor, Washington, 98335, United States
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Puyallup, Washington, 98372, United States
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Tacoma, Washington, 98405, United States
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Traverse City, Michigan, 49684, United States
MyMichigan Medical Center Saginaw

Saginaw, Michigan, 48601, United States
National Jewish Health-Main Campus

Denver, Colorado, 80206, United States
National Jewish Health-Northern Hematology Oncology

Thornton, Colorado, 80260, United States
National Jewish Health-Western Hematology Oncology

Golden, Colorado, 80401, United States
Nebraska Cancer Specialists/Oncology Hematology West PC

Grand Island, Nebraska, 68803, United States
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New Ulm, Minnesota, 56073, United States
Newland Medical Associates-Clarkston

Clarkston, Michigan, 48346, United States
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Pontiac, Michigan, 48341, United States
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Robbinsdale, Minnesota, 55422, United States
Northwell Health Imbert Cancer Center

Bay Shore, New York, 11706, United States
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Lake Success, New York, 11042, United States
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Kennewick, Washington, 99336, United States
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Escanaba, Michigan, 49829, United States
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Mansfield, Ohio, 44903, United States
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Marion, Ohio, 43302, United States
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‘Aiea, Hawaii, 96701, United States
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Paoli, Pennsylvania, 19301, United States
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Saint Louis Park, Minnesota, 55416, United States
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Colorado Springs, Colorado, 80907, United States
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Cedar Rapids, Iowa, 52402, United States
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Greenville, South Carolina, 29605, United States
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Easley, South Carolina, 29640, United States
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Greenville, South Carolina, 29615, United States
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Greenville, South Carolina, 29605, United States
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Greer, South Carolina, 29650, United States
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Clinton, South Carolina, 29325, United States
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Seneca, South Carolina, 29672, United States
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Boiling Springs, South Carolina, 29316, United States
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Honolulu, Hawaii, 96813, United States
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Honolulu, Hawaii, 96817, United States
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‘Aiea, Hawaii, 96701, United States
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Honolulu, Hawaii, 96813, United States
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Asheboro, North Carolina, 27203, United States
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Fort Myers, Florida, 33905, United States
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Saint Paul, Minnesota, 55101, United States
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Willmar, Minnesota, 56201, United States
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Media, Pennsylvania, 19063, United States
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Waconia, Minnesota, 55387, United States
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Columbus, Ohio, 43214, United States
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Denver, Colorado, 80220, United States
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Lone Tree, Colorado, 80124, United States
SMC Center for Hematology Oncology Union

Union, South Carolina, 29379, United States
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Boise, Idaho, 83706, United States
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Caldwell, Idaho, 83605, United States
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Nampa, Idaho, 83687, United States
Saint Ann's Hospital

Westerville, Ohio, 43081, United States
Saint Francis Cancer Center

Greenville, South Carolina, 29607, United States
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Greenville, South Carolina, 29601, United States
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Shakopee, Minnesota, 55379, United States
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Maplewood, Minnesota, 55109, United States
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Denver, Colorado, 80218, United States
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Lexington, Kentucky, 40509, United States
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Green Bay, Wisconsin, 54301, United States
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Marinette, Wisconsin, 54143, United States
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Oconto Falls, Wisconsin, 54154, United States
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Green Bay, Wisconsin, 54303, United States
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Sturgeon Bay, Wisconsin, 54235-1495, United States
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Fargo, North Dakota, 58122, United States
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Fargo, North Dakota, 58122, United States
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Sioux Falls, South Dakota, 57117-5134, United States
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Sioux City, Iowa, 51101, United States
South Carolina Cancer Specialists PC

Hilton Head Island, South Carolina, 29926-3827, United States
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Clinton, North Carolina, 28328, United States
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Goldsboro, North Carolina, 27534, United States
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Jacksonville, North Carolina, 28546, United States
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Springfield, Ohio, 45504, United States
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Springfield, Ohio, 45504, United States
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Honolulu, Hawaii, 96813, United States
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Belpre, Ohio, 45714, United States
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Englewood, Colorado, 80113, United States
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Columbus, Ohio, 43219, United States
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Denver, Colorado, 80209, United States
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Seaford, Delaware, 19973, United States
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Georgetown, South Carolina, 29440, United States
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Cincinnati, Ohio, 45255, United States
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Cincinnati, Ohio, 45247, United States
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Grand Rapids, Michigan, 49503, United States
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Brighton, Michigan, 48114, United States
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Canton, Michigan, 48188, United States
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Chelsea, Michigan, 48118, United States
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Ypsilanti, Michigan, 48197, United States
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Brighton, Michigan, 48114, United States
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Canton, Michigan, 48188, United States
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Pontiac, Michigan, 48341, United States
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Livonia, Michigan, 48154, United States
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Los Angeles, California, 90095, United States
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Des Moines, Iowa, 50309, United States
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Fort Dodge, Iowa, 50501, United States
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Saint Paul, Minnesota, 55102, United States
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Fridley, Minnesota, 55432, United States
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New Orleans, Louisiana, 70112, United States
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Honolulu, Hawaii, 96813, United States
University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912, United States
University of Michigan Health - West

Wyoming, Michigan, 49519, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
Upper Valley Medical Center

Troy, Ohio, 45373, United States
Utah Valley Regional Medical Center

Provo, Utah, 84604, United States
Vince Lombardi Cancer Clinic - Oshkosh

Oshkosh, Wisconsin, 54904, United States
Vince Lombardi Cancer Clinic-Sheboygan

Sheboygan, Wisconsin, 53081, United States
Vince Lombardi Cancer Clinic-Two Rivers

Two Rivers, Wisconsin, 54241, United States
Wayne Hospital

Greenville, Ohio, 45331, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
Willis-Knighton Medical and Cancer Center

Shreveport, Louisiana, 71103, United States

Conditions

Explore the condition pages connected to this study.

BREAST CARCINOMA CERVICAL CARCINOMA OVARIAN CARCINOMA POSTMENOPAUSAL UTERINE CORPUS CANCER VAGINAL CARCINOMA VULVAR CARCINOMA