Which antibiotic works best for hidden anal chlamydia?
NCT ID NCT03532464
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two common antibiotics—azithromycin (single dose) and doxycycline (7-day course)—for treating anal chlamydia in women who also had a vaginal chlamydia infection. The goal was to see which treatment clears the anal infection better, since anal chlamydia often goes unnoticed and can lead to repeat infections. The trial enrolled 460 women and used a DNA test to check if the infection was gone after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- azithromycin and doxycycline
- What this could lead to
- If this trial succeeds, it could show which antibiotic works better for anorectal chlamydia, helping prevent repeat infections and complications like infertility.
- What could go wrong
- This is a completed Phase 4 trial, but results may not apply to all populations. Both drugs are already approved, so the benefit is limited to treatment choice rather than a breakthrough.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHRU Tours
Tours, 37000, France
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CHU de Bordeaux
Bordeaux, 33000, France
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CHU de Nantes
Nantes, 44000, France
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CeGGID - Bordeaux
Bordeaux, 33000, France
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CeGIDD - Marseille
Marseille, Marignane, 13700, France
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Hôpital Hôtel Dieu
Paris, 75004, France
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Hôpital de Roubaix
Roubaix, 59170, France
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