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Back cracking for cramps? study tests spinal therapy for period pain

NCT ID NCT06673537

Symptom relief Sponsor: Istanbul University - Cerrahpasa Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at whether spinal manipulation combined with connective tissue massage can reduce pain, menstrual symptoms, depression, and sleep problems in women with primary dysmenorrhea (painful periods). Seventy-five women were split into three groups: one received both treatments, one got massage with a fake spinal manipulation, and one had no treatment. Over six weeks, researchers measured pain, symptoms, mood, and sleep quality to see if the combo approach helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
spinal manipulation and connective tissue massage
What this could lead to
If effective, this combination therapy could offer a non-drug option to reduce menstrual pain and improve sleep in women with primary dysmenorrhea.
What could go wrong
This is a small, completed observational study with no blinding for the control group. Results may not apply to all women, and the sham group limits conclusions about spinal manipulation's specific effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

75 people

The number who actually took part.

Started

Sep 2024

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being 18 years or older, * Having primary dysmenorrhea according to the criteria specified in the Primary Dysmenorrhea Consensus Guide (1. Onset of pain 6 to 24 months after menarche, 2. Pain lasting between 8 to 72 hours, and 3. The most intense pain occurring on the 1st and/or 2nd day of menstruation), * Having a regular menstrual cycle (28 ± 7 days). Exclusion Criteria: * Having gastrointestinal, urogenital, autoimmune, or psychiatric disorders (serious psychiatric disorders that would prevent participation in the study), * Having other chronic pain syndromes, * Having given birth or a positive pregnancy test, * Using an intrauterine device (IUD), * Having undergone pelvic surgery, * Having used chronic medications, including oral contraceptives or antidepressants, within at least 6 months prior to the study, * Having irregular menstrual cycles (shorter than 21 days or longer than 35 days, and/or a cycle variation exceeding 4 days), * Having a history of pathological conditions indicating secondary dysmenorrhea.

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Conditions

The condition(s) this trial relates to.

dysmenorrhea primary dysmenorrhea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dysmenorrhea Primary dysmenorrhea

Contacts and locations

Locations

  • Istanbul University-Cerrahpasa

    Istanbul, Istanbul, 34500, Turkey (Türkiye)

  • IstanbulUC

    Istanbul, Istanbul, 34500, Turkey (Türkiye)

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