Istanbul University - Cerrahpasa

This study tests whether a 3-month exercise program combining aerobic, strength, and balance training can improve disease activity and daily function in people with multiple sclerosis. Forty participants will do exercises either in person or via video at home. The goal is to see …

This study looks at 60 women aged 18-55 who have low iron stores but normal blood counts. First, they get two months of dietary advice to eat more iron-rich foods. Then, those who still have low iron take an iron pill daily for one month. The goal is to see if this approach can p…

This study looks at whether a special PET scan can find early signs of scarring in the heart muscle of people with ARVC, a rare inherited heart disease that can lead to dangerous heart rhythms. Fifteen adults with ARVC will get this scan along with standard tests. Researchers hop…

This study tests a new way of reading PSMA PET/CT scans, called the Istanbul PSMA PET/CT Criteria, to see if it can better identify which men with low-risk prostate cancer can safely choose active surveillance (monitoring instead of immediate treatment). The researchers will enro…

This study compares virtual reality (VR) relaxation with face-to-face relaxation for pregnant women hospitalized with preeclampsia, a condition causing high blood pressure. Researchers will measure anxiety, comfort, heart rate, and baby's well-being in 96 participants. The goal i…

This study tests whether special education programs can improve quality of life for people with brain tumors and reduce the burden on their caregivers. About 72 patients and their caregivers will take part. Researchers will measure quality of life and caregiver stress before and …

This study compares two manual therapy techniques—Positional Release Technique and Instrument-Assisted Soft Tissue Mobilization—for treating nonspecific neck pain. 51 adults with desk jobs will be randomly assigned to one of the two techniques plus home exercises, or home exercis…

This study tests an accelerated form of transcranial magnetic stimulation (TMS) for people with major depression that hasn't improved with medication. Over five days, 35 adults will receive multiple sessions of targeted brain stimulation. Researchers will track changes in depress…

This study tests whether adding Feldenkrais exercises—a gentle movement approach that boosts body awareness—to standard corrective exercises can improve posture, strength, and neck function in adults with forward head posture. Sixty participants aged 18-65 who spend at least 4 ho…

This study tests whether using a brain activity monitor (BIS) to guide sedation during a procedure that shocks the heart back to normal rhythm leads to faster recovery and fewer side effects. About 60 adults with atrial fibrillation will be randomly assigned to receive sedation g…

This study tests whether a numbing injection (TAP block) given before heart procedures done through the groin can reduce pain and improve patient and doctor satisfaction. About 100 adults having planned heart catheterization or stent placement will be randomly assigned to receive…

This study tests an accelerated form of transcranial magnetic stimulation (TMS) for people with obsessive-compulsive disorder (OCD) who haven't gotten better with standard treatments. Over 7 days, 30 participants will receive 28 sessions of brain stimulation targeting areas linke…

This study tests a set of simple steps to keep newborns warm right after birth, like drying them, putting on a hat, and skin-to-skin contact. The goal is to see if this helps babies stay warm, breathe steadily, and start breastfeeding sooner. The trial will include 140 full-term …

This study tests whether doing thinking tasks (like counting backwards or matching colors) at the same time as physical exercises can improve walking, balance, and memory in teens with pediatric-onset multiple sclerosis. Twenty-two participants aged 12–18 will be randomly assigne…

This study compares two types of exercise—video-game-based 'exergaming' and standard neuromuscular training—in 60 adults aged 65+ who have Motor Cognitive Risk Syndrome, a condition that raises the risk of dementia. The goal is to see which approach better improves walking, balan…

This study is testing whether adding breathing exercises to balance training can improve thinking skills in people aged 65 and older. Forty participants will do 30 minutes of balance exercises plus 15 minutes of breathing exercises twice a week for 8 weeks. Researchers will measu…

This study tests whether adding mental tasks to treadmill walking (dual-task training) improves movement, thinking, and daily living skills more than walking alone. It involves 46 people with early-to-mid stage Alzheimer's who can already walk. The goal is to see if this combined…

This study looks at how tai chi and yoga affect flexibility, anxiety, and sleep in healthy women aged 18 to 45. Participants will do either tai chi or yoga for 8 weeks, twice a week. Researchers will measure changes using simple tests and questionnaires to see which activity offe…

This study tests whether giving morphine during coronary artery bypass surgery can improve pain control and reduce side effects like nausea after the operation. Sixty adults scheduled for elective heart surgery will be randomly assigned to receive either morphine or no additional…

This study looks at whether telling people to focus on their muscles (internal focus) or on an external object (external focus) during knee exercises leads to better strength and less pain. Researchers will enroll 36 adults with patellofemoral pain syndrome and track their progre…

This pilot study tests whether a mental exercise program called Graded Motor Imagery can help people with chronic ankle instability. Over six days, participants will practice ankle recognition tasks, imagine moving their ankle, and use mirror therapy. The study compares results b…

This study compares two types of foot exercises for adults with flexible flat feet. One group does traditional short foot exercises, while the other uses biofeedback—a device that gives real-time feedback on foot movement. The goal is to see which approach better improves foot po…

This study will observe 60 adults having heart bypass surgery to see if a higher dose of the anesthetic propofol reduces nausea and vomiting after the operation. Researchers will compare patients who get high-dose propofol to those who get a low dose. Participants will be checked…

This study tests whether adding a gentle nerve stimulation device (tVNS) to standard exercises can reduce pain and improve movement in people with frozen shoulder. Forty adults aged 40-65 will receive either active tVNS or a sham device during 6 weeks of supervised rehab. Researc…

This study looks at whether teaching people about their rotator cuff-related shoulder pain can reduce symptoms without other treatments. Researchers will track pain levels and knowledge in 116 adults aged 18-65. The goal is to find out which patients improve most from education a…

This study tests whether using virtual reality (VR) to train patients before colorectal cancer surgery can lower their anxiety, boost their readiness, and speed up recovery. About 68 adults will be split into three groups: one gets VR training, another gets a written brochure, an…

This study tests whether combining a gentle nerve stimulation (taVNS) with robot-assisted arm training helps stroke survivors regain arm function better than robot training alone. Thirty adults who had a stroke at least 6 months ago and have moderate to severe arm weakness will p…

This study tests whether a gentle nerve stimulation (taVNS) combined with robot-assisted arm training can help stroke survivors regain arm movement, breathing strength, and quality of life. Thirty adults who had a stroke at least six months ago will receive either real or fake st…

This study tests whether doing core exercises through video games (exergaming) works as well as standard core exercises for children aged 8-13 with juvenile idiopathic arthritis. Both groups will exercise twice a week for 12 weeks. The goal is to see which approach better improve…

This study tests if Schroth exercises, a special type of physical therapy, can improve shoulder muscle function in children aged 7-18 with a rounded upper back (thoracic hyperkyphosis). 56 participants will either do these exercises for 8 weeks or receive standard posture educati…

This study tests whether warm sacral massage using cherry pit pouches and partner-assisted showers can reduce pain and improve the birth experience for first-time mothers. 150 women in active labor will be randomly assigned to massage, shower, or standard care. Pain levels and co…

This study looks at whether detailed heart scans (echocardiograms and MRIs) can improve how doctors predict short-term risks in people with a type of high blood pressure in the lungs (pulmonary arterial hypertension). Researchers will follow 50 adults for 6 months to see if addin…

This study watches 100 adults having lung surgery to see if one type of anesthesia leads to faster recovery. Patients get either a computer-controlled IV drip or inhaled gas, based on their doctor's usual practice. Researchers track how quickly patients wake up, breathe on their …

This study watches how blood flows to the kidneys in 51 adults having elective minimally invasive abdominal surgery. Researchers use two non-invasive tools—ultrasound and light sensors—to measure kidney function at key times during and after surgery. The goal is to see if these t…

This study is testing whether a walking test called the Dynamic Gait Index (DGI) is a reliable way to measure walking difficulties in children with juvenile idiopathic arthritis (JIA). Researchers will compare 26 children with JIA to 26 healthy children, all aged 8-16. The goal i…

This study looks at a new, less invasive way to monitor blood flow during heart ablation procedures. Doctors will use a special device to track heart function beat-by-beat. The goal is to see if this method helps improve care for 27 adult patients having heart ablation.

This study looks at what limits social activities in adults with hand injuries and tests whether a 10-15 minute video from a physiotherapist can improve their knowledge and awareness. About 40 participants will answer questionnaires before and right after watching the video. The …

This study looks at whether combining two simple measures—a breathing test (RSBI) and a blood-based score (CALLY)—can better predict when ICU patients are ready to come off a breathing machine. About 105 adults will be followed for up to 7 days after the tube is removed. The goal…

This study is for people aged 65 and older who are admitted to the intensive care unit (ICU). Researchers want to see if three simple health scores can predict the risk of dying in the ICU. The goal is to help doctors better understand which older patients need the most urgent ca…

This study looks at 100 ICU patients with shock who are on a breathing machine. Doctors will use an ultrasound to measure the size of a vein and artery in the leg. They want to see if this ratio can tell whether giving fluids will help the heart pump more blood. The goal is to fi…

This study is creating a new tool that uses photographs to assess how shoulder pain affects everyday activities like reaching or lifting. Researchers will test the scale on 100 people with shoulder pain lasting more than three months. The goal is to provide a clearer, patient-fri…

This study compares two ways of giving anesthesia during brain surgery: a computer-controlled pump versus manual control by the anesthesiologist. The goal is to see which method leads to less postoperative delirium (confusion), pain, and nausea. Researchers will study 70 adults h…

This study looks at how often small areas of the lung collapse (atelectasis) during surgery when patients lie face-up versus face-down. Researchers will use lung ultrasound, a safe and radiation-free imaging method, to check lung health right after anesthesia and just before waki…

This study aims to translate and test a tool that measures how much parents and future parents know about toxic chemicals in the environment and how those chemicals might affect children's development. Researchers will ask 204 adults to fill out surveys to see if the Turkish vers…

This study looks at whether early heart ultrasound results can predict which patients hospitalized with heart failure will need to return to the hospital or have a higher risk of death. Researchers will measure heart structure and function before starting IV diuretics in 76 adult…

This study looks at how support from a partner influences parenting confidence and depression risk in first-time mothers. Researchers will survey 193 women who are within 12 months of giving birth. The goal is to understand whether partner support helps protect against postpartum…

This study looks at how implantable heart devices like pacemakers, ICDs, and CRT devices may affect the right side of the heart. Researchers will check 40 adults before and 6 months after device placement using heart scans, ultrasound, and a blood test. No experimental treatment …

This study aims to better understand hidden hearing loss, a condition where people struggle to hear in noisy places despite normal standard hearing tests. Researchers will measure brain responses to sound and test speech understanding in noise in 63 adults. The goal is to see if …

This study is testing whether a new questionnaire, called the Postural Habits and Awareness Scale (PHAS), reliably measures how aware people with postural hyperkyphosis (rounded upper back) are of their posture. 128 participants will fill out the questionnaire twice, two weeks ap…

This study tests a special nutrition program for ICU patients after their breathing tube is removed. The program uses a tool called GUSS-ICU to guide safe eating and drinking for four days. Researchers will check if it helps reduce risks like malnutrition, dehydration, and pneumo…