New brain zaps could lift depression in days
NCT ID NCT07603804
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests an accelerated form of transcranial magnetic stimulation (TMS) for people with major depression that hasn't improved with medication. Over five days, 35 adults will receive multiple sessions of targeted brain stimulation. Researchers will track changes in depression symptoms and measure blood markers to understand how the treatment works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- accelerated intermittent theta burst stimulation (iTBS) using a device
- What this could lead to
- If successful, this could point toward a faster, non-drug treatment option for people with depression that hasn't responded to standard medications.
- What could go wrong
- This is a small, early-stage study with only 35 participants, so results may not apply to everyone. The treatment may not work for all, and side effects like headache or discomfort are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Istanbul University - Cerrahpasa
RECRUITINGIstanbul, 34000, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could a new drug offer hope for Treatment-Resistant depression?
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- Targeting depression: can MRI-Guided brain zaps rewire key circuits?
- One-Day brain zaps: a new hope for stubborn depression?