Sugar solution may rival steroids for stuck fingers
NCT ID NCT07681804
First seen Jul 02, 2026 · Last updated Jul 29, 2026 · Updated 4 times
Summary
This study compares two ultrasound-guided injections for trigger finger, a condition where a finger gets stuck in a bent position. One injection uses betamethasone (a steroid), the other uses dextrose (a sugar solution). The goal is to see if dextrose, which may help tissue heal, works as well as the standard steroid treatment. Adults with trigger finger for at least four weeks can join, and the study measures pain, finger locking, and hand function over 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- betamethasone and dextrose injections
- What this could lead to
- If dextrose works as well as betamethasone, it could offer a safer, regenerative option for trigger finger without steroid side effects.
- What could go wrong
- This is a small, early-stage trial with only 42 participants, so results may not apply broadly. Dextrose may prove less effective than the standard steroid treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 42 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18 and 75 years * Clinical diagnosis of trigger finger * Presence of symptoms for at least 4 weeks Exclusion Criteria: * Previous surgery on the affected finger * Injection treatment to the affected finger within the previous 3 months * Active local or systemic infection * Active malignancy * Active inflammatory rheumatic disease (e.g., rheumatoid arthritis, ankylosing spondylitis, polymyalgia rheumatica, vasculitis) * Uncontrolled diabetes mellitus and/or uncontrolled hypertension * Autoimmune connective tissue diseases (e.g., systemic lupus erythematosus, antiphospholipid syndrome, systemic sclerosis, Sjögren syndrome, polymyositis, dermatomyositis, adult-onset Still's disease) * Coagulopathy that increases the risk of injection procedures * Pregnancy * Known allergy or hypersensitivity to lidocaine, betamethasone, or dextrose * Mental impairment or severe psychiatric disorder that may interfere with study participation or informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine
RECRUITINGIstanbul, 34098, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can light therapy unlock stiff fingers?
- Numbing patch eases injection pain for trigger finger sufferers
- Hand rehab revolution? early data may predict recovery months ahead
- Shock waves or a splint? new study tests better fix for stuck fingers
- Which works best for trigger finger: injection or minor surgery?
- Which incision is best for trigger finger? new study aims to find out