Heart surgery patients may get better pain relief with morphine during operation

NCT ID NCT07472959

Recruiting now Symptom relief Sponsor: Istanbul University - Cerrahpasa Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving morphine during coronary artery bypass surgery can improve pain control and reduce side effects like nausea after the operation. Sixty adults scheduled for elective heart surgery will be randomly assigned to receive either morphine or no additional morphine during the procedure. Researchers will measure pain levels and side effects in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: morphine
What this could lead to: If it works, this could show that giving morphine during heart surgery helps control pain better and reduces side effects like nausea afterward.
What could go wrong: This is a small, single-center trial with only 60 people, so results may not apply to everyone. Morphine can cause nausea, vomiting, and breathing problems.

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Conditions

The condition(s) this trial relates to.

agnosia coronary artery disorder Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC SURGERY PATIENT PAIN AFTER SURGERY POSTOPERATIVE PAIN

Contacts and locations

Locations

Istanbul University -Cerrahpasa Institute of Cardiology
RECRUITING

Istanbul, Outside of the US, 34000, Turkey (Türkiye)

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