Heart surgery patients may get better pain relief with morphine during operation

NCT ID NCT07472959

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving morphine during coronary artery bypass surgery can improve pain control and reduce side effects like nausea after the operation. Sixty adults scheduled for elective heart surgery will be randomly assigned to receive either morphine or no additional morphine during the procedure. Researchers will measure pain levels and side effects in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

morphine

What this could lead to

If it works, this could show that giving morphine during heart surgery helps control pain better and reduces side effects like nausea afterward.

What could go wrong

This is a small, single-center trial with only 60 people, so results may not apply to everyone. Morphine can cause nausea, vomiting, and breathing problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia coronary artery disorder Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Istanbul University -Cerrahpasa Institute of Cardiology

    RECRUITING

    Istanbul, Outside of the US, 34000, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••