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A safer first cut? trial tests two laparoscopic entry points for endometrial cancer surgery

NCT ID NCT07725159

Disease control Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Jul 28, 2026 · Updated 2 times

Summary

This trial compares two ways to make the first incision for laparoscopic surgery in women with endometrial cancer: the standard umbilical entry versus entry through the Lee-Huang point, a spot on the upper left abdomen. The goal is to see which approach leads to fewer complications and more reliable access. About 200 women scheduled for laparoscopic surgery are taking part, and the results could help surgeons choose the safest starting point.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Laparoscopic entry through the Lee-Huang point or the umbilicus
What this could lead to
If one entry method proves safer or more reliable, it could become the preferred technique for laparoscopic surgery in endometrial cancer, reducing complications.
What could go wrong
This is a single-center trial, and results may not apply to all patients or surgical settings. The study compares two specific entry points, not other aspects of surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

202 people

The number who actually took part.

Started

Apr 2024

Finished

Apr 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients aged 18 years or older. * Scheduled for elective laparoscopic gynecologic surgery. * Eligible for laparoscopic abdominal entry through either the Lee-Huang point or the umbilical entry site. * Provided written informed consent. Exclusion Criteria: * Pregnancy. * Emergency surgery. * Previous upper abdominal surgery precluding safe Lee-Huang point or umbilical entry. * Contraindication to laparoscopy. * Refusal or inability to provide informed consent.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometrial cancer

Contacts and locations

Locations

  • University of Health Sciences Turkey, Kartal Dr. Lütfi Kırdar City Hospital

    Istanbul, Istanbul, 34865, Turkey (Türkiye)

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