Why is endometrial cancer often advanced in brazil? a new study digs into the data
NCT ID NCT06014580
First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time
Summary
This observational study will examine the molecular and epidemiological characteristics of endometrial cancer in Brazil, focusing on women diagnosed between 2016 and 2019. Researchers will analyze tumor samples for genetic mutations and biomarkers, and collect data on demographics, treatment patterns, and outcomes. The goal is to understand why advanced disease is common and to generate knowledge that could guide future clinical trials and improve care for this population.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal why endometrial cancer is often advanced in Brazil and point toward targeted therapies and better treatment strategies for this population.
- What could go wrong
- This is an observational study, so it will not test any new treatment. The findings may not apply beyond the Brazilian population studied, and the data depends on the quality of medical records and tumor samples.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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276 people
The number who actually took part.
- Started
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Nov 2023
- Finished
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Oct 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Women diagnosed with endometrial cancer between January 2016 and December 2019 at participating research sites.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women ≥18 years * Histological diagnosis of endometrial carcinoma. * Diagnosis of endometrial cancer between January 2016 and December 2019. * FIGO (International Federation of Gynecology and Obstetrics, 2018) Stage I - IV. * Site and investigator with access to a medical record chart from which data can be abstracted. * Presence of a sample of tumor tissue (primary tumor or metastasis) available for biomarker testing. Exclusion Criteria: * Noninvasive endometrial cancer. * Patients with a history of concurrent or previously treated non-endometrial malignancies except for appropriately treated 1) non -metastatic non-melanoma skin cancer and/or 2) non-metastatic low-grade thyroid tumors and/or 3) in situ carcinomas, including cervix, colon, and skin. * Nonepithelial histology (leiomyosarcoma, adenosarcoma, endometrial stromal sarcoma, undifferentiated sarcoma, or other mesenchymal tumors.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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BP - A Beneficência Portuguesa de São Paulo
São Paulo, São Paulo, 01323-030, Brazil
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Clinica Prognóstica - Centro de Pesquisa Clínica Onconeo
Campo Grande, Mato Grosso do Sul, 79.002-061, Brazil
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Hospital Evangélico de Cachoeiro de Itapemirim - Centro de Pesquisas Clínicas em Oncologia (CPCO)
Cachoeiro de Itapemirim, Espírito Santo, 29.308-065, Brazil
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Hospital Napoleão Laureano
João Pessoa, Paraíba, 58013-140, Brazil
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Hospital de Oncologia do Maranhão Dr. Tarquínio Lopes Filho
São Luís, Maranhão, 65015-460, Brazil
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ICC - Instituto do Câncer do Ceará
Fortaleza, Ceará, 60.430-230, Brazil
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INCA - Instituto Nacional de Câncer
Rio de Janeiro, Rio de Janeiro, 20.230-130, Brazil
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Instituto do Câncer Brasil - Unidade Três Lagoas
Três Lagoas, Mato Grosso do Sul, 79.601-001, Brazil
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Santa Casa de Misericórdia de Feira de Santana
Feira de Santana, Estado de Bahia, Brazil
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UOPECCAN - Hospital do Câncer de Cascavel
Cascavel, Santa Catarina, 85.806-300, Brazil
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